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Zdhhc9 Gene Detail
Summary
  • Symbol
    Zdhhc9
  • Name
    zinc finger, DHHC domain containing 9
  • Synonyms
    9530098M12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444393
    NCBI Gene: 208884
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:47260846-47297755 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 25.55 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    779 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444393
 protein coding gene ChrX:47260844-47297792 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035689
 protein coding gene ChrX:43305406-43343845 (-)
A/J MGP_AJ_G0035672
 protein coding gene ChrX:43180978-43219348 (-)
AKR/J MGP_AKRJ_G0035592
 protein coding gene ChrX:44363279-44409788 (-)
BALB/cJ MGP_BALBcJ_G0035658
 protein coding gene ChrX:42833769-42870736 (-)
C3H/HeJ MGP_C3HHeJ_G0035362
 protein coding gene ChrX:43607629-43644390 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036187
 protein coding gene ChrX:44336514-44375464 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033039
 protein coding gene ChrX:40881035-40917927 (-)
CAST/EiJ MGP_CASTEiJ_G0034653
 protein coding gene ChrX:31190629-31227079 (-)
CBA/J MGP_CBAJ_G0035336
 protein coding gene ChrX:45575793-45614081 (-)
DBA/2J MGP_DBA2J_G0035490
 protein coding gene ChrX:43029597-43065294 (-)
FVB/NJ MGP_FVBNJ_G0035439
 protein coding gene ChrX:42736972-42773238 (-)
LP/J MGP_LPJ_G0035578
 protein coding gene ChrX:43671657-43709013 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035477
 protein coding gene ChrX:46988514-47034805 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036205
 protein coding gene ChrX:43219159-43255547 (-)
PWK/PhJ MGP_PWKPhJ_G0034352
 protein coding gene ChrX:30673976-30712476 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034197
 protein coding gene ChrX:31975902-32011919 (-)
WSB/EiJ MGP_WSBEiJ_G0034797
 protein coding gene ChrX:42843362-42891417 (-)



Homology
more
  • Human Ortholog
    ZDHHC9, zinc finger DHHC-type palmitoyltransferase 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZDHHC9, zinc finger DHHC-type palmitoyltransferase 9
  • Synonyms
    CGI89, CXorf11, DHHC9, MMSA1, MRXSR, MRXSZ, ZDHHC10, ZNF379, ZNF380
  • Links
    NCBI Gene ID: 51114
    neXtProt AC: NX_Q9Y397
    UniProt: Q9Y397

  • Chr Location
    Xq26.1; chrX:129803288-129843909 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Zdhhc9 mouse models; 1 with human ZDHHC9 associations

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Null males exhibit decreased body weight, hypotonia, decreased anxiety, spatial learning deficits, decreased acoustic startle response and decreased corpus callosum volume.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    79
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036985 Ensembl Gene Model | MGI Sequence Detail 36910 C57BL/6J ±  kb
    transcript ENSMUST00000037960 Ensembl | MGI Sequence Detail 2982 Not Applicable  
    polypeptide ENSMUSP00000044734 Ensembl | MGI Sequence Detail 364 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 79
      cDNA 79

      Microarray probesets 6
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 6
      Phenotypes 13
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:352419 Balasubramanian A, et al., The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Sci Immunol. 2024 Apr 12;9(94):eadn1452
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory