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Dnah14 Gene Detail
Summary
  • Symbol
    Dnah14
  • Name
    dynein, axonemal, heavy chain 14
  • Synonyms
    A230079K17Rik, Dnahc14, Gm980, LOC381311
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444525
    NCBI Gene: 240960
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:181404158-181642306 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 84.83 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5459 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444525
protein coding gene Chr1:181404124-181643339 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016887
protein coding gene Chr1:188297577-188328682 (+)
A/J MGP_AJ_G0016866
protein coding gene Chr1:180652693-180686432 (+)
AKR/J MGP_AKRJ_G0016832
protein coding gene Chr1:186025329-186055980 (+)
BALB/cJ MGP_BALBcJ_G0016824
protein coding gene Chr1:181292945-181324162 (+)
C3H/HeJ MGP_C3HHeJ_G0016649
protein coding gene Chr1:186807526-186837667 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017287
protein coding gene Chr1:194406314-194439431 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014994
protein coding gene Chr1:171622080-171650741 (+)
CAST/EiJ MGP_CASTEiJ_G0016230
protein coding gene Chr1:186165116-186196058 (+)
CBA/J MGP_CBAJ_G0016623
protein coding gene Chr1:201585736-201615507 (+)
DBA/2J MGP_DBA2J_G0016729
protein coding gene Chr1:179463230-179493820 (+)
FVB/NJ MGP_FVBNJ_G0016725
protein coding gene Chr1:177579706-177610627 (+)
LP/J MGP_LPJ_G0016803
protein coding gene Chr1:189520192-189551225 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016756
protein coding gene Chr1:208677897-208708905 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017324
protein coding gene Chr1:185828428-185860543 (+)
PWK/PhJ MGP_PWKPhJ_G0016018
protein coding gene Chr1:178613075-178642381 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015794
protein coding gene Chr1:184769226-184797939 (+)
WSB/EiJ MGP_WSBEiJ_G0016293
protein coding gene Chr1:186019344-186052986 (+)



Homology
more
  • Human Ortholog
    DNAH14, dynein axonemal heavy chain 14
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DNAH14, dynein axonemal heavy chain 14
  • Synonyms
    C1orf67, Dnahc14, HL-18, HL18
  • Links
    NCBI Gene ID: 127602
    neXtProt AC: NX_Q0VDD8
    UniProt: Q0VDD8

  • Chr Location
    1q42.12

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 240960 NCBI Gene Model | MGI Sequence Detail 238149 C57BL/6J ±  kb
transcript NM_001377039 RefSeq | MGI Sequence Detail 13992 C57BL/6  
polypeptide NP_001363968 RefSeq | MGI Sequence Detail 4599 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    6 Sequences
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR026983 Dynein heavy chain
    IPR043157 Dynein heavy chain, AAA1 domain, small subdomain
    IPR041466 Dynein heavy chain, AAA 5 extension domain
    IPR041658 Dynein heavy chain AAA lid domain
    IPR042219 Dynein heavy chain AAA lid domain superfamily
    IPR024317 Dynein heavy chain, AAA module D4
    IPR035706 Dynein heavy chain, ATP-binding dynein motor region
    IPR024743 Dynein heavy chain, coiled coil stalk
    IPR041228 Dynein heavy chain, C-terminal domain
    IPR043160 Dynein heavy chain, C-terminal domain, barrel region
    IPR042222 Dynein heavy chain, domain 2, N-terminal
    IPR035699 Dynein heavy chain, hydrolytic ATP-binding dynein motor region
    IPR013602 Dynein heavy chain, linker
    IPR042228 Dynein heavy chain, linker, subdomain 3
    IPR004273 Dynein heavy chain region D6 P-loop domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7
Other
Accession IDs
less
MGI:2685826
References
more
  • Summaries
    All 17
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory