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Fhip1a Gene Detail
Summary
  • Symbol
    Fhip1a
  • Name
    FHF complex subunit HOOK interacting protein 1A
  • Synonyms
    9930021J17Rik, Fam160a1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444746
    NCBI Gene: 229488
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr3:85567370-85653516 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 37.83 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2261 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444746
 protein coding gene Chr3:85567368-85724598 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027349
 protein coding gene Chr3:85662949-85832841 (-)
A/J MGP_AJ_G0027313
 protein coding gene Chr3:82778144-82935854 (-)
AKR/J MGP_AKRJ_G0027279
 protein coding gene Chr3:84742837-84907579 (-)
BALB/cJ MGP_BALBcJ_G0027322
 protein coding gene Chr3:82855442-83016394 (-)
C3H/HeJ MGP_C3HHeJ_G0027066
 protein coding gene Chr3:85055757-85225199 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027768
 protein coding gene Chr3:88849099-89019922 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025121
 protein coding gene Chr3:78426434-78582487 (-)
CAST/EiJ MGP_CASTEiJ_G0026513
 protein coding gene Chr3:85250037-85414577 (-)
CBA/J MGP_CBAJ_G0027041
 protein coding gene Chr3:91816705-91987324 (-)
DBA/2J MGP_DBA2J_G0027177
 protein coding gene Chr3:82274568-82432318 (-)
FVB/NJ MGP_FVBNJ_G0027145
 protein coding gene Chr3:80576136-80734904 (-)
LP/J MGP_LPJ_G0027285
 protein coding gene Chr3:86605264-86771855 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027164
 protein coding gene Chr3:98085020-98267347 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027826
 protein coding gene Chr3:84538056-84701181 (-)
PWK/PhJ MGP_PWKPhJ_G0026247
 protein coding gene Chr3:82070535-82228503 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026063
 protein coding gene Chr3:83701628-83866461 (-)
WSB/EiJ MGP_WSBEiJ_G0026591
 protein coding gene Chr3:84913090-85076137 (-)



Homology
more
  • Human Ortholog
    FHIP1A, FHF complex subunit HOOK interacting protein 1A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FHIP1A, FHF complex subunit HOOK interacting protein 1A
  • Synonyms
    FAM160A1, FHIP-L
  • Links
    NCBI Gene ID: 729830
    neXtProt AC: NX_Q05DH4
    UniProt: Q05DH4

  • Chr Location
    4q31.3; chr4:151409176-151670503 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit defects in placentation with abnormal trophoblast layer formation, abnormal trophoblast giant cell size and morphology, and complete lethality throughout fetal growth and development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    24
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 229488 NCBI Gene Model | MGI Sequence Detail 86147 C57BL/6J ±  kb
    transcript NM_172682 RefSeq | MGI Sequence Detail 4392 C57BL/6  
    polypeptide Q505K2 UniProt | EBI | MGI Sequence Detail 1081 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000032026 FHF complex subunit HOOK-interacting protein 1A
      (term hierarchy)
    • InterPro Domains
      IPR019384 FHF complex subunit HOOK interacting protein
      IPR045669 FHF complex subunit HOOK-interacting protein, C-terminal
      IPR045668 FHF complex subunit HOOK-interacting protein, KELAA motif
    Molecular
    Reagents
    less
    • All nucleic 24
      cDNA 24

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:6715945
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 2
      Phenotypes 14
    • Earliest
      J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory