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Ptgr3 Gene Detail
Summary
  • Symbol
    Ptgr3
  • Name
    prostaglandin reductase 3
  • Synonyms
    C530046K17Rik, Pthr3, Zadh2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444835
    NCBI Gene: 225791
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:84106250-84115579 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 57.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    254 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444835
 protein coding gene Chr18:84106188-84115653 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024605
 protein coding gene Chr18:85225707-85235905 (+)
A/J MGP_AJ_G0024572
 protein coding gene Chr18:81475270-81484555 (+)
AKR/J MGP_AKRJ_G0024543
 protein coding gene Chr18:83897297-83908024 (+)
BALB/cJ MGP_BALBcJ_G0024570
 protein coding gene Chr18:81666008-81675631 (+)
C3H/HeJ MGP_C3HHeJ_G0024339
 protein coding gene Chr18:84020531-84030035 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025017
 protein coding gene Chr18:87342882-87353293 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022448
 protein coding gene Chr18:80185424-80194695 (+)
CAST/EiJ MGP_CASTEiJ_G0023812
 protein coding gene Chr18:84356005-84367346 (+)
CBA/J MGP_CBAJ_G0024309
 protein coding gene Chr18:90479927-90489331 (+)
DBA/2J MGP_DBA2J_G0024439
 protein coding gene Chr18:80995531-81005201 (+)
FVB/NJ MGP_FVBNJ_G0024405
 protein coding gene Chr18:80320903-80330628 (+)
LP/J MGP_LPJ_G0024523
 protein coding gene Chr18:85025889-85037143 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024435
 protein coding gene Chr18:91713181-91723619 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025066
 protein coding gene Chr18:84093708-84103027 (+)
PWK/PhJ MGP_PWKPhJ_G0023557
 protein coding gene Chr18:81386148-81395913 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023363
 protein coding gene Chr18:84141479-84150774 (+)
WSB/EiJ MGP_WSBEiJ_G0023874
 protein coding gene Chr18:84060325-84070616 (+)



Homology
more
  • Human Ortholog
    PTGR3, prostaglandin reductase 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PTGR3, prostaglandin reductase 3
  • Synonyms
    PRG-3, PTGR-3, ZADH2
  • Links
    NCBI Gene ID: 284273
    neXtProt AC: NX_Q8N4Q0
    UniProt: Q8N4Q0

  • Chr Location
    18q22.3; chr18:75195108-75209139 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 225791 NCBI Gene Model | MGI Sequence Detail 9330 C57BL/6J ±  kb
transcript NM_001417840 RefSeq | MGI Sequence Detail 3701 C57BL/6  
polypeptide Q8BGC4 UniProt | EBI | MGI Sequence Detail 377 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 4
Other
Accession IDs
less
MGI:7413983
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:200769 Yu YH, et al., Prostaglandin reductase-3 negatively modulates adipogenesis through regulation of PPARgamma activity. J Lipid Res. 2013 Sep;54(9):2391-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory