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Ckap4 Gene Detail
Summary
  • Symbol
    Ckap4
  • Name
    cytoskeleton-associated protein 4
  • Synonyms
    5630400A09Rik, CLIMP-63, P63
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444926
    NCBI Gene: 216197
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:84362169-84369752 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 41.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    265 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444926
 protein coding gene Chr10:84362169-84369926 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017591
 protein coding gene Chr10:85399123-85406854 (-)
A/J MGP_AJ_G0017571
 protein coding gene Chr10:82499238-82506969 (-)
AKR/J MGP_AKRJ_G0017530
 protein coding gene Chr10:84790097-84797828 (-)
BALB/cJ MGP_BALBcJ_G0017534
 protein coding gene Chr10:82748688-82756419 (-)
C3H/HeJ MGP_C3HHeJ_G0017356
 protein coding gene Chr10:84874319-84882050 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017991
 protein coding gene Chr10:88290646-88298377 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015675
 protein coding gene Chr10:78323303-78330963 (-)
CAST/EiJ MGP_CASTEiJ_G0016923
 protein coding gene Chr10:84726231-84733977 (-)
CBA/J MGP_CBAJ_G0017326
 protein coding gene Chr10:91996505-92004236 (-)
DBA/2J MGP_DBA2J_G0017432
 protein coding gene Chr10:81642310-81650041 (-)
FVB/NJ MGP_FVBNJ_G0017426
 protein coding gene Chr10:80874766-80882497 (-)
LP/J MGP_LPJ_G0017504
 protein coding gene Chr10:86036305-86044036 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017454
 protein coding gene Chr10:93595236-93602967 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018028
 protein coding gene Chr10:84712373-84720107 (-)
PWK/PhJ MGP_PWKPhJ_G0016704
 protein coding gene Chr10:81501493-81509239 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016493
 protein coding gene Chr10:83336615-83345947 (-)
WSB/EiJ MGP_WSBEiJ_G0016982
 protein coding gene Chr10:84704626-84712348 (-)



Homology
more
  • Human Ortholog
    CKAP4, cytoskeleton associated protein 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CKAP4, cytoskeleton associated protein 4
  • Synonyms
    CLIMP-63, CLIMP63, ERGIC-63, p63
  • Links
    NCBI Gene ID: 10970
    neXtProt AC: NX_Q07065
    UniProt: Q07065

  • Chr Location
    12q23.3; chr12:106237881-106304279 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    770
  • Tissues
    41
  • cDNA Data
    127
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 216197 NCBI Gene Model | MGI Sequence Detail 7584 C57BL/6J ±  kb
transcript NM_175451 RefSeq | MGI Sequence Detail 2915 C57BL/6  
polypeptide Q8BMK4 UniProt | EBI | MGI Sequence Detail 575 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 128
    cDNA 127
    Primer pair 1

    Microarray probesets 10
References
more
  • Summaries
    All 49
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 16
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory