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Utp14b Gene Detail
Summary
  • Symbol
    Utp14b
  • Name
    UTP14B small subunit processome component
  • Synonyms
    4932411L21Rik, jsd
  • Feature Type
    protein coding gene
  • IDs
    MGI:2445092
    NCBI Gene: 195434
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:78635600-78645305 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 40.84 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    70 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2445092
 protein coding gene Chr1:78635600-78649229 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016202
 protein coding gene Chr1:79400546-79415677 (+)
A/J MGP_AJ_G0016185
 protein coding gene Chr1:76621257-76634655 (+)
AKR/J MGP_AKRJ_G0016142
 protein coding gene Chr1:78696094-78709563 (+)
BALB/cJ MGP_BALBcJ_G0016140
 protein coding gene Chr1:76711261-76724646 (+)
C3H/HeJ MGP_C3HHeJ_G0015970
 protein coding gene Chr1:79069810-79084630 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016593
 protein coding gene Chr1:82452801-82466275 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014313
 protein coding gene Chr1:72044563-72057859 (+)
CAST/EiJ MGP_CASTEiJ_G0015555
 protein coding gene Chr1:78454114-78467566 (+)
CBA/J MGP_CBAJ_G0015944
 protein coding gene Chr1:85168839-85185494 (+)
DBA/2J MGP_DBA2J_G0016045
 protein coding gene Chr1:75933338-75950189 (+)
FVB/NJ MGP_FVBNJ_G0016048
 protein coding gene Chr1:75091946-75105425 (+)
LP/J MGP_LPJ_G0016117
 protein coding gene Chr1:80530017-80546928 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016068
 protein coding gene Chr1:88389016-88403145 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016640
 protein coding gene Chr1:78845123-78859557 (+)
PWK/PhJ MGP_PWKPhJ_G0015341
 protein coding gene Chr1:75402854-75416330 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015119
 protein coding gene Chr1:78173022-78186579 (+)
WSB/EiJ MGP_WSBEiJ_G0015616
 protein coding gene Chr1:78630111-78643996 (+)



Homology
more
  • Human Ortholog
    UTP14A, UTP14A small subunit processome component
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UTP14A, UTP14A small subunit processome component
  • Synonyms
    dJ537K23.3, NYCO16, SDCCAG16, Utp14
  • Links
    NCBI Gene ID: 10813
    neXtProt AC: NX_Q9BVJ6
    UniProt: Q9BVJ6

  • Chr Location
    Xq26.1; chrX:129906121-129929761 (+)  GRCh38
  • Human Ortholog
    UTP14C, UTP14C small subunit processome component
  • Synonyms
    2700066J21Rik, KIAA0266, UTP14B
  • Links
    NCBI Gene ID: 9724
    neXtProt AC: NX_Q5TAP6
    UniProt: Q5TAP6

  • Chr Location
    13q14.3; chr13:52024691-52033600 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 2 genetic backgrounds
    34 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous males are sterile with spermatogonial arrest and elevated intratesticular testosterone levels.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 195434 NCBI Gene Model | MGI Sequence Detail 9706 C57BL/6J ±  kb
    transcript NM_001136226 RefSeq | MGI Sequence Detail 3702 ZRU/MplStud  
    polypeptide Q6EJB6 UniProt | EBI | MGI Sequence Detail 756 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 7

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGD-MRK-11533, MGI:96642
    References
    more
    • Summaries
      All 55
      Gene Ontology 6
      Phenotypes 34
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:229199 Song HW, et al., shRNA off-target effects in vivo: impaired endogenous siRNA expression and spermatogenic defects. PLoS One. 2015;10(3):e0118549
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/29/2024
    MGI 6.24     		The Jackson Laboratory