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Lrif1 Gene Detail
Summary
  • Symbol
    Lrif1
  • Name
    ligand dependent nuclear receptor interacting factor 1
  • Synonyms
    2010012G17Rik, 4933421E11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2445214
    NCBI Gene: 321000
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:106592303-106643893 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 46.52 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    931 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2445214
 protein coding gene Chr3:106592256-106643893 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027736
 protein coding gene Chr3:108141185-108195342 (+)
A/J MGP_AJ_G0027696
 protein coding gene Chr3:104724136-104775506 (+)
AKR/J MGP_AKRJ_G0027661
 protein coding gene Chr3:107276184-107330014 (+)
BALB/cJ MGP_BALBcJ_G0027708
 protein coding gene Chr3:104421560-104474736 (+)
C3H/HeJ MGP_C3HHeJ_G0027438
 protein coding gene Chr3:107612989-107661861 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028152
 protein coding gene Chr3:112184967-112239265 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025490
 protein coding gene Chr3:100904307-100950445 (+)
CAST/EiJ MGP_CASTEiJ_G0026894
 protein coding gene Chr3:106985075-107034573 (+)
CBA/J MGP_CBAJ_G0027413
 protein coding gene Chr3:115979398-116030100 (+)
DBA/2J MGP_DBA2J_G0027555
 protein coding gene Chr3:103922304-103972456 (+)
FVB/NJ MGP_FVBNJ_G0027523
 protein coding gene Chr3:101818917-101867022 (+)
LP/J MGP_LPJ_G0027662
 protein coding gene Chr3:109532243-109603970 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027553
 protein coding gene Chr3:122074638-122140899 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028207
 protein coding gene Chr3:106837568-106889082 (+)
PWK/PhJ MGP_PWKPhJ_G0026620
 protein coding gene Chr3:103656313-103702537 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026440
 protein coding gene Chr3:104989469-105040634 (+)
WSB/EiJ MGP_WSBEiJ_G0026974
 protein coding gene Chr3:107398418-107448107 (+)



Homology
more
  • Human Ortholog
    LRIF1, ligand dependent nuclear receptor interacting factor 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRIF1, ligand dependent nuclear receptor interacting factor 1
  • Synonyms
    C1orf103, FSHD3, HBiX1, RIF1
  • Links
    NCBI Gene ID: 55791
    neXtProt AC: NX_Q5T3J3
    UniProt: Q5T3J3

  • Chr Location
    1p13.3; chr1:110874957-110963965 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human LRIF1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    8
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Lrif1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    32 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    88
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056260 Ensembl Gene Model | MGI Sequence Detail 51591 C57BL/6J ±  kb
transcript ENSMUST00000098750 Ensembl | MGI Sequence Detail 3103 Not Applicable  
polypeptide ENSMUSP00000096346 Ensembl | MGI Sequence Detail 755 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000030510 ligand-dependent nuclear receptor-interacting factor 1
    (term hierarchy)
  • InterPro Domains
    IPR026191 Ligand-dependent nuclear receptor-interacting factor 1
  • GlyGen
    Q8CDD9 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 88
    cDNA 88

    Microarray probesets 5
Other
Accession IDs
less
MGI:1919314, MGI:2139718
References
more
  • Summaries
    All 37
    Diseases 1
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory