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Suox Gene Detail
Summary
  • Symbol
    Suox
  • Name
    sulfite oxidase
  • Synonyms
    MGC:28458, SO
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446117
    NCBI Gene: 211389
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:128505756-128509787 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 77.12 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    142 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446117
 protein coding gene Chr10:128505756-128509942 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017876
 protein coding gene Chr10:132434969-132439000 (-)
A/J MGP_AJ_G0017851
 protein coding gene Chr10:127117655-127121686 (-)
AKR/J MGP_AKRJ_G0017814
 protein coding gene Chr10:130835941-130839972 (-)
BALB/cJ MGP_BALBcJ_G0017815
 protein coding gene Chr10:127485503-127489534 (-)
C3H/HeJ MGP_C3HHeJ_G0017638
 protein coding gene Chr10:131002717-131006748 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018270
 protein coding gene Chr10:136911920-136915951 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015948
 protein coding gene Chr10:121034428-121038465 (-)
CAST/EiJ MGP_CASTEiJ_G0017199
 protein coding gene Chr10:131724220-131728250 (-)
CBA/J MGP_CBAJ_G0017608
 protein coding gene Chr10:142489650-142493681 (-)
DBA/2J MGP_DBA2J_G0017714
 protein coding gene Chr10:126179153-126183184 (-)
FVB/NJ MGP_FVBNJ_G0017709
 protein coding gene Chr10:125094542-125098573 (-)
LP/J MGP_LPJ_G0017788
 protein coding gene Chr10:133027279-133031310 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017737
 protein coding gene Chr10:145063879-145067910 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018310
 protein coding gene Chr10:130940286-130944317 (-)
PWK/PhJ MGP_PWKPhJ_G0016984
 protein coding gene Chr10:126434227-126438258 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016773
 protein coding gene Chr10:130053490-130057518 (-)
WSB/EiJ MGP_WSBEiJ_G0017258
 protein coding gene Chr10:131161078-131165109 (-)



Homology
more
  • Human Ortholog
    SUOX, sulfite oxidase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SUOX, sulfite oxidase
  • Links
    NCBI Gene ID: 6821
    neXtProt AC: NX_P51687
    UniProt: P51687

  • Chr Location
    12q13.2; chr12:55997180-56006641 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human SUOX associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    93
  • cDNA Data
    49
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 211389 NCBI Gene Model | MGI Sequence Detail 4032 C57BL/6J ±  kb
transcript NM_173733 RefSeq | MGI Sequence Detail 2349 Not Specified  
polypeptide Q8R086 UniProt | EBI | MGI Sequence Detail 546 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000015833 sulfite oxidase, mitochondrial
    (term hierarchy)
  • EC
    1.8.3.1
  • InterPro Domains
    IPR018506 Cytochrome b5, heme-binding site
    IPR001199 Cytochrome b5-like heme/steroid binding domain
    IPR036400 Cytochrome b5-like heme/steroid binding domain superfamily
    IPR008335 Eukaryotic molybdopterin oxidoreductase
    IPR014756 Immunoglobulin E-set
    IPR005066 Moybdenum cofactor oxidoreductase, dimerisation
    IPR000572 Oxidoreductase, molybdopterin-binding domain
    IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily
    IPR022407 Oxidoreductase, molybdopterin binding site
  • GlyGen
    Q8R086 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 50
    cDNA 49
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 9
    Phenotypes 5
  • Earliest
    J:86816 Mootha VK, et al., Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell. 2003 Nov 26;115(5):629-40
  • Latest
    J:348785 Zhang D, et al., Maternal Ezh1/2 deficiency impairs the function of mitochondria in mouse oocytes and early embryos. J Cell Physiol. 2024 Mar 26;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory