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Fam120a Gene Detail
Summary
  • Symbol
    Fam120a
  • Name
    family with sequence similarity 120, member A
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446163
    NCBI Gene: 218236
  • Alliance
    gene page
  • Transcription Start Sites
    18 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:49032695-49121493 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 25.00 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1414 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446163
 protein coding gene Chr13:49032692-49121754 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020528
 protein coding gene Chr13:47821167-47916882 (-)
A/J MGP_AJ_G0020482
 protein coding gene Chr13:46127647-46219340 (-)
AKR/J MGP_AKRJ_G0020459
 protein coding gene Chr13:47424718-47516778 (-)
BALB/cJ MGP_BALBcJ_G0020478
 protein coding gene Chr13:46343747-46434505 (-)
C3H/HeJ MGP_C3HHeJ_G0020277
 protein coding gene Chr13:47251473-47344705 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020911
 protein coding gene Chr13:49263226-49361093 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018496
 protein coding gene Chr13:44119570-44205289 (-)
CAST/EiJ MGP_CASTEiJ_G0019792
 protein coding gene Chr13:47258340-47349515 (-)
CBA/J MGP_CBAJ_G0020238
 protein coding gene Chr13:51309693-51411580 (-)
DBA/2J MGP_DBA2J_G0020360
 protein coding gene Chr13:45655583-45746077 (-)
FVB/NJ MGP_FVBNJ_G0020339
 protein coding gene Chr13:45168220-45257951 (-)
LP/J MGP_LPJ_G0020435
 protein coding gene Chr13:48044045-48139856 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020368
 protein coding gene Chr13:51039419-51136457 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020954
 protein coding gene Chr13:47130635-47223798 (-)
PWK/PhJ MGP_PWKPhJ_G0019548
 protein coding gene Chr13:45822884-45915765 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019376
 protein coding gene Chr13:45836040-45924484 (-)
WSB/EiJ MGP_WSBEiJ_G0019854
 protein coding gene Chr13:47439507-47531702 (-)



Homology
more
  • Human Ortholog
    FAM120A, family with sequence similarity 120 member A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM120A, family with sequence similarity 120 member A
  • Synonyms
    C9orf10, HBVPTPAP, OSSA
  • Links
    NCBI Gene ID: 23196
    neXtProt AC: NX_Q9NZB2
    UniProt: Q9NZB2

  • Chr Location
    9q22.31; chr9:93451685-93566112 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    744
  • Tissues
    25
  • cDNA Data
    200
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038014 Ensembl Gene Model | MGI Sequence Detail 88799 C57BL/6J ±  kb
    transcript ENSMUST00000060805 Ensembl | MGI Sequence Detail 5105 Not Applicable  
    polypeptide ENSMUSP00000053877 Ensembl | MGI Sequence Detail 1112 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000032357 constitutive coactivator of PPAR-gamma-like protein 1
      (term hierarchy)
    • InterPro Domains
      IPR026784 Constitutive coactivator of PPAR-gamma
      IPR029060 PIN-like domain superfamily
    • GlyGen
      Q6A0A9 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 201
      cDNA 201

      Microarray probesets 6
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 4
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory