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Lpgat1 Gene Detail
Summary
  • Symbol
    Lpgat1
  • Name
    lysophosphatidylglycerol acyltransferase 1
  • Synonyms
    MGC:18768
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446186
    NCBI Gene: 226856
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:191449946-191516367 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 96.78 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1331 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446186
 protein coding gene Chr1:191449682-191516367 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016947
 protein coding gene Chr1:198781335-198854172 (+)
A/J MGP_AJ_G0016926
 protein coding gene Chr1:190626734-190693801 (+)
AKR/J MGP_AKRJ_G0016891
 protein coding gene Chr1:196295986-196366382 (+)
BALB/cJ MGP_BALBcJ_G0016884
 protein coding gene Chr1:191307674-191375098 (+)
C3H/HeJ MGP_C3HHeJ_G0016708
 protein coding gene Chr1:197133855-197206754 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017347
 protein coding gene Chr1:205120257-205196645 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015054
 protein coding gene Chr1:181529418-181595597 (+)
CAST/EiJ MGP_CASTEiJ_G0016291
 protein coding gene Chr1:196730900-196799526 (+)
CBA/J MGP_CBAJ_G0016682
 protein coding gene Chr1:212715357-212795084 (+)
DBA/2J MGP_DBA2J_G0016788
 protein coding gene Chr1:189346239-189418277 (+)
FVB/NJ MGP_FVBNJ_G0016784
 protein coding gene Chr1:187474443-187542402 (+)
LP/J MGP_LPJ_G0016863
 protein coding gene Chr1:199972640-200045310 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016816
 protein coding gene Chr1:219384541-219458797 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017384
 protein coding gene Chr1:196154039-196226432 (+)
PWK/PhJ MGP_PWKPhJ_G0016078
 protein coding gene Chr1:188641319-188712261 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015854
 protein coding gene Chr1:195167259-195229386 (+)
WSB/EiJ MGP_WSBEiJ_G0016353
 protein coding gene Chr1:196388370-196471624 (+)



Homology
more
  • Human Ortholog
    LPGAT1, lysophosphatidylglycerol acyltransferase 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LPGAT1, lysophosphatidylglycerol acyltransferase 1
  • Synonyms
    FAM34A, FAM34A1, LPLAT7, NET8
  • Links
    NCBI Gene ID: 9926
    neXtProt AC: NX_Q92604
    UniProt: Q92604

  • Chr Location
    1q32.3; chr1:211743457-211830763 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    802
  • Tissues
    96
  • cDNA Data
    13
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000026623 Ensembl Gene Model | MGI Sequence Detail 66422 C57BL/6J ±  kb
    transcript ENSMUST00000110856 Ensembl | MGI Sequence Detail 2792 Not Applicable  
    polypeptide ENSMUSP00000106480 Ensembl | MGI Sequence Detail 409 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 10
    Other
    Accession IDs
    less
    MGI:2138316, MGI:2138562
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 2
      Gene Ontology 7
      Phenotypes 10
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/29/2024
    MGI 6.24     		The Jackson Laboratory