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Kif26b Gene Detail
Summary
  • Symbol
    Kif26b
  • Name
    kinesin family member 26B
  • Synonyms
    D230039L06Rik, N-11 kinesin
  • Feature Type
    protein coding gene
  • IDs
    MGI:2447076
    NCBI Gene: 269152
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:178356690-178766765 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 83.16 cM, cytoband H3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    11761 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2447076
 protein coding gene Chr1:178356690-178766765 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016857
 protein coding gene Chr1:184838375-185268424 (+)
A/J MGP_AJ_G0016835
 protein coding gene Chr1:177392030-177811418 (+)
AKR/J MGP_AKRJ_G0016801
 protein coding gene Chr1:182680994-183099010 (+)
BALB/cJ MGP_BALBcJ_G0016793
 protein coding gene Chr1:178023490-178436279 (+)
C3H/HeJ MGP_C3HHeJ_G0016618
 protein coding gene Chr1:183414325-183841557 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017257
 protein coding gene Chr1:190847565-191283766 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014964
 protein coding gene Chr1:168401957-168804757 (+)
CAST/EiJ MGP_CASTEiJ_G0016199
 protein coding gene Chr1:182718502-183150259 (+)
CBA/J MGP_CBAJ_G0016592
 protein coding gene Chr1:197965097-198409160 (+)
DBA/2J MGP_DBA2J_G0016698
 protein coding gene Chr1:176246809-176658588 (+)
FVB/NJ MGP_FVBNJ_G0016694
 protein coding gene Chr1:174327021-174740165 (+)
LP/J MGP_LPJ_G0016772
 protein coding gene Chr1:186114960-186544743 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016725
 protein coding gene Chr1:205145853-205579845 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017293
 protein coding gene Chr1:182403845-182831840 (+)
PWK/PhJ MGP_PWKPhJ_G0015987
 protein coding gene Chr1:175311931-175730477 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015763
 protein coding gene Chr1:181349927-181791463 (+)
WSB/EiJ MGP_WSBEiJ_G0016262
 protein coding gene Chr1:182623013-183057845 (+)



Homology
more
  • Human Ortholog
    KIF26B, kinesin family member 26B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KIF26B, kinesin family member 26B
  • Links
    NCBI Gene ID: 55083
    neXtProt AC: NX_Q2KJY2
    UniProt: Q2KJY2

  • Chr Location
    1q44; chr1:245154985-245709432 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 3 alleles in 3 genetic backgrounds
    2 phenotypes from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit neonatal lethality with impaired kidney development due to loss of cortical nephrogenic zone mesenchyme and failure of ureteric buds to invade and branch into the mesenchyme.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    849
  • Tissues
    44
  • cDNA Data
    12
  • Literature Summary
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 269152 NCBI Gene Model | MGI Sequence Detail 410076 C57BL/6J ±  kb
    transcript NM_001161665 RefSeq | MGI Sequence Detail 7422 ZRU/MplStud  
    polypeptide Q7TNC6 UniProt | EBI | MGI Sequence Detail 2112 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 12

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:3045335, MGI:3607707
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 10
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:70760 Miki H, et al., All kinesin superfamily protein, KIF, genes in mouse and human. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7004-11
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory