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Bicral Gene Detail
Summary
  • Symbol
    Bicral
  • Name
    BRD4 interacting chromatin remodeling complex associated protein like
  • Synonyms
    BC032203, Gltscr1l, mKIAA0240
  • Feature Type
    protein coding gene
  • IDs
    MGI:2673855
    NCBI Gene: 210982
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:47109046-47169408 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 22.90 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1951 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2673855
 protein coding gene Chr17:47109046-47201329 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023835
 protein coding gene Chr17:47896564-47931773 (-)
A/J MGP_AJ_G0023793
 protein coding gene Chr17:46732445-46766973 (-)
AKR/J MGP_AKRJ_G0023764
 protein coding gene Chr17:47088313-47123176 (-)
BALB/cJ MGP_BALBcJ_G0023797
 protein coding gene Chr17:46632872-46668392 (-)
C3H/HeJ MGP_C3HHeJ_G0023560
 protein coding gene Chr17:47833380-47873419 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024240
 protein coding gene Chr17:49943365-49979984 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021690
 protein coding gene Chr17:43507000-43540153 (-)
CAST/EiJ MGP_CASTEiJ_G0023042
 protein coding gene Chr17:47923338-47966159 (-)
CBA/J MGP_CBAJ_G0023537
 protein coding gene Chr17:51750860-51790701 (-)
DBA/2J MGP_DBA2J_G0023663
 protein coding gene Chr17:45500011-45535141 (-)
FVB/NJ MGP_FVBNJ_G0023630
 protein coding gene Chr17:45131946-45166058 (-)
LP/J MGP_LPJ_G0023744
 protein coding gene Chr17:48566395-48604357 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023659
 protein coding gene Chr17:51275158-51314643 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024285
 protein coding gene Chr17:47441436-47479475 (-)
PWK/PhJ MGP_PWKPhJ_G0022786
 protein coding gene Chr17:44843056-44879444 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022602
 protein coding gene Chr17:44329639-44369909 (-)
WSB/EiJ MGP_WSBEiJ_G0023107
 protein coding gene Chr17:48003288-48046700 (-)



Homology
more
  • Human Ortholog
    BICRAL, BICRA like chromatin remodeling complex associated protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BICRAL, BICRA like chromatin remodeling complex associated protein
  • Synonyms
    GLTSCR1L, KIAA0240, SMARCK2
  • Links
    NCBI Gene ID: 23506
    neXtProt AC: NX_Q6AI39
    UniProt: Q6AI39

  • Chr Location
    6p21.1; chr6:42746339-42868558 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele display abnormal embryo turning, embryonic growth retardation, cardiac hypertrophy, and complete embryonic lethality during organogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    10
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036568 Ensembl Gene Model | MGI Sequence Detail 60363 C57BL/6J ±  kb
    transcript ENSMUST00000040624 Ensembl | MGI Sequence Detail 6575 Not Applicable  
    polypeptide ENSMUSP00000044833 Ensembl | MGI Sequence Detail 1074 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000059849 BRD4-interacting chromatin-remodeling complex-associated protein-like
      (term hierarchy)
    • InterPro Domains
      IPR052438 Chromatin-remodeling and transcription coactivator
      IPR015671 GLTSCR protein, conserved domain
    • GlyGen
      Q8CHH5 3 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (2 sites)
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 10
      Primer pair 1
      Other 1

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:5883604
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory