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Mir124a-1 Gene Detail
Summary
  • Symbol
    Mir124a-1
  • Name
    microRNA 124a-1
  • Synonyms
    Mirn124a, Mirn124a-1, mmu-mir-124-1, mmu-mir-124a-1
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676807
    NCBI Gene: 387233
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:64828106-64828190 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 33.77 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    43 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676807
 miRNA gene Chr14:64828106-64828190 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008132
 miRNA gene Chr14:59153153-59153237 (+)
A/J MGP_AJ_G0008119
 miRNA gene Chr14:57801539-57801623 (+)
AKR/J MGP_AKRJ_G0008097
 miRNA gene Chr14:59828093-59828177 (+)
BALB/cJ MGP_BALBcJ_G0008101
 miRNA gene Chr14:57749791-57749875 (+)
C3H/HeJ MGP_C3HHeJ_G0008045
 miRNA gene Chr14:59462559-59462643 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008291
 miRNA gene Chr14:61909059-61909143 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007382
 miRNA gene Chr14:55740556-55740640 (+)
CAST/EiJ MGP_CASTEiJ_G0007923
 miRNA gene Chr14:55943651-55943735 (+)
CBA/J MGP_CBAJ_G0008013
 miRNA gene Chr14:63782351-63782435 (+)
DBA/2J MGP_DBA2J_G0008049
 miRNA gene Chr14:57466041-57466125 (+)
FVB/NJ MGP_FVBNJ_G0008072
 miRNA gene Chr14:56861892-56861976 (+)
LP/J MGP_LPJ_G0008132
 miRNA gene Chr14:60188083-60188167 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008041
 miRNA gene Chr14:62943510-62943594 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008287
 miRNA gene Chr14:58993223-58993307 (+)
PWK/PhJ MGP_PWKPhJ_G0007844
 miRNA gene Chr14:54151717-54151801 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007740
 miRNA gene Chr14:54954143-54954227 (+)
WSB/EiJ MGP_WSBEiJ_G0008000
 miRNA gene Chr14:59307175-59307259 (+)



Homology
more
  • Human Ortholog
    MIR124-1, microRNA 124-1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR124-1, microRNA 124-1
  • Synonyms
    mir-124-1, MIR124A, MIR124A1, MIRN124-1, MIRN124A1
  • Links
    NCBI Gene ID: 406907

  • Chr Location
    chr8:9903388-9903472 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted mutation exhibit impaired hippocampal axogenesis and retinal cone cell survival.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    857
  • Tissues
    80
  • Literature Summary
    51
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      23
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 387233 NCBI Gene Model | MGI Sequence Detail 85 C57BL/6J ±  kb
    transcript NR_029813 RefSeq | MGI Sequence Detail 85 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 20
      Primer pair 8
      Other 12
    Other Database
    Links
    less
    miRBase MI0000716
    References
    more
    • Summaries
      All 81
      Developmental Gene Expression 51
      Gene Ontology 5
      Phenotypes 7
    • Earliest
      J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
    • Latest
      J:349888 Zhang J, et al., m(5)C methylated lncRncr3-MeCP2 interaction restricts miR124a-initiated neurogenesis. Nat Commun. 2024 Jun 15;15(1):5136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory