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Bahcc1 Gene Detail
Summary
  • Symbol
    Bahcc1
  • Name
    BAH domain and coiled-coil containing 1
  • Synonyms
    MGC:79150
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679272
    NCBI Gene: 268515
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:120123773-120183108 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 83.96 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1131 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2679272
 protein coding gene Chr11:120123696-120183123 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019493
 protein coding gene Chr11:124682001-124745113 (+)
A/J MGP_AJ_G0019461
 protein coding gene Chr11:119137960-119201588 (+)
AKR/J MGP_AKRJ_G0019431
 protein coding gene Chr11:122718390-122778787 (+)
BALB/cJ MGP_BALBcJ_G0019436
 protein coding gene Chr11:119494867-119555597 (+)
C3H/HeJ MGP_C3HHeJ_G0019242
 protein coding gene Chr11:123053286-123115695 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019885
 protein coding gene Chr11:128458481-128518815 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017510
 protein coding gene Chr11:116142633-116203472 (+)
CAST/EiJ MGP_CASTEiJ_G0018796
 protein coding gene Chr11:124529525-124594677 (+)
CBA/J MGP_CBAJ_G0019213
 protein coding gene Chr11:133480546-133547907 (+)
DBA/2J MGP_DBA2J_G0019325
 protein coding gene Chr11:118508804-118568517 (+)
FVB/NJ MGP_FVBNJ_G0019317
 protein coding gene Chr11:118201087-118262536 (+)
LP/J MGP_LPJ_G0019397
 protein coding gene Chr11:124985862-125050733 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019350
 protein coding gene Chr11:132325754-132393881 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019924
 protein coding gene Chr11:123405681-123464371 (+)
PWK/PhJ MGP_PWKPhJ_G0018562
 protein coding gene Chr11:119934304-119995025 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018354
 protein coding gene Chr11:123172896-123236190 (+)
WSB/EiJ MGP_WSBEiJ_G0018848
 protein coding gene Chr11:123402458-123464823 (+)



Homology
more
  • Human Ortholog
    BAHCC1, BAH domain and coiled-coil containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BAHCC1, BAH domain and coiled-coil containing 1
  • Synonyms
    BAHD2
  • Links
    NCBI Gene ID: 57597
    neXtProt AC: NX_Q9P281
    UniProt: Q9P281

  • Chr Location
    17q25.3; chr17:81395457-81466331 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene results in perinatal lethality for the majority of mutants. Those that survive exhibit hind leg motor dysfunction.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    753
  • Tissues
    34
  • cDNA Data
    66
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039741 Ensembl Gene Model | MGI Sequence Detail 59336 C57BL/6J ±  kb
transcript ENSMUST00000122148 Ensembl | MGI Sequence Detail 10712 Not Applicable  
polypeptide ENSMUSP00000112827 Ensembl | MGI Sequence Detail 2643 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000030197 BAH and coiled-coil domain-containing protein 1
    (term hierarchy)
  • PDB
    6VIL
  • InterPro Domains
    IPR047411 BAH and coiled-coil domain-containing protein 1, Tudor domain
    IPR048924 BAHCC1-like, Tudor domain
    IPR052429 BAH domain-containing protein
    IPR001025 Bromo adjacent homology (BAH) domain
    IPR043151 Bromo adjacent homology (BAH) domain superfamily
  • GlyGen
    Q3UHR0 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 66
    cDNA 66

    Microarray probesets 1
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:345950 Li J, et al., Transmembrane protein TMEM97 and epigenetic reader BAHCC1 constitute an axis that supports pro-inflammatory cytokine expression. Cell Signal. 2024 Apr;116:111069
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory