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Zfp395 Gene Detail
Summary
  • Symbol
    Zfp395
  • Name
    zinc finger protein 395
  • Synonyms
    BC027382, LOC380912, MGC:60757
  • Feature Type
    protein coding gene
  • IDs
    MGI:2682318
    NCBI Gene: 380912
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:65595838-65636379 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 34.32 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    974 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2682318
 protein coding gene Chr14:65595796-65636379 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021479
 protein coding gene Chr14:59958006-60000793 (+)
A/J MGP_AJ_G0021438
 protein coding gene Chr14:58573581-58614466 (+)
AKR/J MGP_AKRJ_G0021414
 protein coding gene Chr14:60607496-60648953 (+)
BALB/cJ MGP_BALBcJ_G0021444
 protein coding gene Chr14:58509671-58550232 (+)
C3H/HeJ MGP_C3HHeJ_G0021221
 protein coding gene Chr14:60253717-60294842 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021883
 protein coding gene Chr14:62738825-62779076 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019423
 protein coding gene Chr14:56503910-56544528 (+)
CAST/EiJ MGP_CASTEiJ_G0020738
 protein coding gene Chr14:56732933-56776247 (+)
CBA/J MGP_CBAJ_G0021188
 protein coding gene Chr14:64631426-64671522 (+)
DBA/2J MGP_DBA2J_G0021311
 protein coding gene Chr14:58222543-58264021 (+)
FVB/NJ MGP_FVBNJ_G0021290
 protein coding gene Chr14:57623187-57663544 (+)
LP/J MGP_LPJ_G0021386
 protein coding gene Chr14:60996699-61039586 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021319
 protein coding gene Chr14:63740662-63781077 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021906
 protein coding gene Chr14:59787401-59828037 (+)
PWK/PhJ MGP_PWKPhJ_G0020482
 protein coding gene Chr14:54930131-54971484 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020315
 protein coding gene Chr14:55763615-55790441 (+)
WSB/EiJ MGP_WSBEiJ_G0020791
 protein coding gene Chr14:60099959-60141864 (+)



Homology
more
  • Human Ortholog
    ZNF395, zinc finger protein 395
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF395, zinc finger protein 395
  • Synonyms
    HDBP-2, HDBP2, HDRF-2, PBF, PRF-1, PRF1, Si-1-8-14
  • Links
    NCBI Gene ID: 55893
    neXtProt AC: NX_Q9H8N7
    UniProt: Q9H8N7

  • Chr Location
    8p21.1; chr8:28345590-28402701 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    733
  • Tissues
    20
  • cDNA Data
    77
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034522 Ensembl Gene Model | MGI Sequence Detail 40542 C57BL/6J ±  kb
    transcript ENSMUST00000066994 Ensembl | MGI Sequence Detail 4229 Not Applicable  
    polypeptide ENSMUSP00000064422 Ensembl | MGI Sequence Detail 508 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • InterPro Domains
      IPR052253 CR1/CR2 motif-containing transcription regulator
      IPR031940 Domain of unknown function DUF4772
      IPR013087 Zinc finger C2H2-type
    Molecular
    Reagents
    less
    • All nucleic 77
      cDNA 77

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2685756, MGI:3039574
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 12
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/17/2024
    MGI 6.24     		The Jackson Laboratory