About   Help   FAQ
Qrich2 Gene Detail
Summary
  • Symbol
    Qrich2
  • Name
    glutamine rich 2
  • Synonyms
    LOC217341
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684912
    NCBI Gene: 217341
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:116332151-116357067 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 81.30 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    655 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684912
 protein coding gene Chr11:116332149-116357092 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019428
 protein coding gene Chr11:120550857-120566637 (-)
A/J MGP_AJ_G0019396
 protein coding gene Chr11:115283619-115298387 (-)
AKR/J MGP_AKRJ_G0019367
 protein coding gene Chr11:118721663-118735557 (-)
BALB/cJ MGP_BALBcJ_G0019371
 protein coding gene Chr11:115690589-115704552 (-)
C3H/HeJ MGP_C3HHeJ_G0019177
 protein coding gene Chr11:119068657-119083929 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019820
 protein coding gene Chr11:124245656-124259581 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017444
 protein coding gene Chr11:112289288-112304199 (-)
CAST/EiJ MGP_CASTEiJ_G0018732
 protein coding gene Chr11:120441395-120455417 (-)
CBA/J MGP_CBAJ_G0019148
 protein coding gene Chr11:129151257-129169092 (-)
DBA/2J MGP_DBA2J_G0019260
 protein coding gene Chr11:114716621-114730476 (-)
FVB/NJ MGP_FVBNJ_G0019252
 protein coding gene Chr11:114224427-114238587 (-)
LP/J MGP_LPJ_G0019330
 protein coding gene Chr11:120936571-120953048 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019285
 protein coding gene Chr11:128212806-128227636 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019859
 protein coding gene Chr11:119376614-119390535 (-)
PWK/PhJ MGP_PWKPhJ_G0018496
 protein coding gene Chr11:116034262-116048529 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018289
 protein coding gene Chr11:119130523-119143833 (-)
WSB/EiJ MGP_WSBEiJ_G0018784
 protein coding gene Chr11:119346988-119362451 (-)



Homology
more
  • Human Ortholog
    QRICH2, glutamine rich 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    QRICH2, glutamine rich 2
  • Synonyms
    SPGF35
  • Links
    NCBI Gene ID: 84074
    neXtProt AC: NX_Q9H0J4
    UniProt: Q9H0J4

  • Chr Location
    17q25.1; chr17:76274049-76310964 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human QRICH2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit male infertility associated with decreased epididymis weight, multiple morphological abnormalities of the sperm flagella, oligozoospermia, and asthenozoospermia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000070331 Ensembl Gene Model | MGI Sequence Detail 24917 C57BL/6J ±  kb
    transcript ENSMUST00000208602 Ensembl | MGI Sequence Detail 7260 Not Applicable  
    polypeptide ENSMUSP00000147009 Ensembl | MGI Sequence Detail 2337 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 12

      Microarray probesets 2
    References
    more
    • Summaries
      All 21
      Gene Ontology 4
      Phenotypes 1
    • Earliest
      J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
    • Latest
      J:270177 Shen Y, et al., Loss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella. Nat Commun. 2019 Jan 25;10(1):433
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory