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Macc1 Gene Detail
Summary
  • Symbol
    Macc1
  • Name
    metastasis associated in colon cancer 1
  • Synonyms
    4732474O15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685113
    NCBI Gene: 238455
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:119354133-119430669 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 63.48 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1772 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685113
 protein coding gene Chr12:119278005-119433722 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020191
 protein coding gene Chr12:122447605-122473987 (+)
A/J MGP_AJ_G0020147
 protein coding gene Chr12:117938869-117972407 (+)
AKR/J MGP_AKRJ_G0020122
 protein coding gene Chr12:121509985-121534523 (+)
BALB/cJ MGP_BALBcJ_G0020130
 protein coding gene Chr12:118367992-118395115 (+)
C3H/HeJ MGP_C3HHeJ_G0019934
 protein coding gene Chr12:121815124-121841992 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020577
 protein coding gene Chr12:126271777-126299382 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018189
 protein coding gene Chr12:114277018-114300061 (+)
CAST/EiJ MGP_CASTEiJ_G0019474
 protein coding gene Chr12:115664442-115690074 (+)
CBA/J MGP_CBAJ_G0019901
 protein coding gene Chr12:131238239-131286192 (+)
DBA/2J MGP_DBA2J_G0020018
 protein coding gene Chr12:117348069-117371657 (+)
FVB/NJ MGP_FVBNJ_G0020003
 protein coding gene Chr12:115968575-115992864 (+)
LP/J MGP_LPJ_G0020092
 protein coding gene Chr12:122437972-122461100 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020039
 protein coding gene Chr12:134570452-134606102 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020606
 protein coding gene Chr12:120691877-120718968 (+)
PWK/PhJ MGP_PWKPhJ_G0019236
 protein coding gene Chr12:112087112-112108086 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019041
 protein coding gene Chr12:113625478-113649050 (+)
WSB/EiJ MGP_WSBEiJ_G0019532
 protein coding gene Chr12:121666350-121692651 (+)



Homology
more
  • Human Ortholog
    MACC1, MET transcriptional regulator MACC1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MACC1, MET transcriptional regulator MACC1
  • Synonyms
    7A5, SH3BP4L
  • Links
    NCBI Gene ID: 346389
    neXtProt AC: NX_Q6ZN28
    UniProt: Q6ZN28

  • Chr Location
    7p21.1; chr7:20134655-20217404 (-)  GRCh38
Human Diseases
less
  • References
    4 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    62 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 238455 NCBI Gene Model | MGI Sequence Detail 76537 C57BL/6J ±  kb
transcript NM_001163136 RefSeq | MGI Sequence Detail 3818 C57BL/6  
polypeptide NP_001156608 RefSeq | MGI Sequence Detail 851 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 82
    Developmental Gene Expression 1
    Diseases 4
    Gene Ontology 2
    Phenotypes 62
  • Earliest
    J:42265 Huang TT, et al., Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys. 1997 Aug 15;344(2):424-32
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory