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Ccnb1ip1 Gene Detail
Summary
  • Symbol
    Ccnb1ip1
  • Name
    cyclin B1 interacting protein 1
  • Synonyms
    Hei10, LOC239083, mei4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685134
    NCBI Gene: 239083
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:51026706-51033185 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 26.25 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    180 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685134
 protein coding gene Chr14:51026705-51045189 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021257
 protein coding gene Chr14:44734541-44741769 (-)
A/J MGP_AJ_G0021211
 protein coding gene Chr14:43401067-43407484 (-)
AKR/J MGP_AKRJ_G0021187
 protein coding gene Chr14:45030309-45036725 (-)
BALB/cJ MGP_BALBcJ_G0021214
 protein coding gene Chr14:43514835-43521248 (-)
C3H/HeJ MGP_C3HHeJ_G0020996
 protein coding gene Chr14:44855198-44861604 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021650
 protein coding gene Chr14:46549608-46556087 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019203
 protein coding gene Chr14:42741959-42748022 (-)
CAST/EiJ MGP_CASTEiJ_G0020520
 protein coding gene Chr14:41916639-41923053 (-)
CBA/J MGP_CBAJ_G0020963
 protein coding gene Chr14:48038010-48044418 (-)
DBA/2J MGP_DBA2J_G0021087
 protein coding gene Chr14:43297305-43303832 (-)
FVB/NJ MGP_FVBNJ_G0021068
 protein coding gene Chr14:42924007-42930435 (-)
LP/J MGP_LPJ_G0021155
 protein coding gene Chr14:45016195-45022600 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021096
 protein coding gene Chr14:47521359-47527785 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021680
 protein coding gene Chr14:44523527-44531180 (-)
PWK/PhJ MGP_PWKPhJ_G0020270
 protein coding gene Chr14:40195608-40202195 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020095
 protein coding gene Chr14:40684108-40691972 (-)
WSB/EiJ MGP_WSBEiJ_G0020573
 protein coding gene Chr14:44715700-44722110 (-)



Homology
more
  • Human Ortholog
    CCNB1IP1, cyclin B1 interacting protein 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCNB1IP1, cyclin B1 interacting protein 1
  • Synonyms
    C14orf18, HEI10
  • Links
    NCBI Gene ID: 57820
    neXtProt AC: NX_Q9NPC3
    UniProt: Q9NPC3

  • Chr Location
    14q11.2; chr14:20311368-20333312 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 2 alleles in 2 genetic backgrounds
    1 images
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced mutation have abnormal testicular and ovarian morphology and exhibit sterility in both sexes owing to meiotic defects.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    725
  • Tissues
    13
  • cDNA Data
    7
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 239083 NCBI Gene Model | MGI Sequence Detail 6480 C57BL/6J ±  kb
    transcript NM_001111119 RefSeq | MGI Sequence Detail 1508 C57BL/6  
    polypeptide D3Z3K2 UniProt | EBI | MGI Sequence Detail 276 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 7
      Primer pair 3

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:3050546
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 4
      Gene Ontology 8
      Phenotypes 20
    • Earliest
      J:86161 Ward JO, et al., Toward the genetics of mammalian reproduction: induction and mapping of gametogenesis mutants in mice. Biol Reprod. 2003 Nov;69(5):1615-25
    • Latest
      J:346630 Zhang X, et al., Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature. Commun Biol. 2024 Mar 23;7(1):363
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory