About   Help   FAQ
Gm614 Gene Detail
Summary
  • Symbol
    Gm614
  • Name
    predicted gene 614
  • Synonyms
    LOC245536
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685460
    NCBI Gene: 245536
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:100304982-100307598 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 43.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    56 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685460
 protein coding gene ChrX:100304979-100307598 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035954
 protein coding gene ChrX:97760677-97763293 (-)
A/J MGP_AJ_G0035939
 protein coding gene ChrX:97766541-97769157 (-)
AKR/J MGP_AKRJ_G0035855
 protein coding gene ChrX:100565549-100568165 (-)
BALB/cJ MGP_BALBcJ_G0035922
 protein coding gene ChrX:96505933-96508549 (-)
C3H/HeJ MGP_C3HHeJ_G0035631
 protein coding gene ChrX:98167414-98170030 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036451
 protein coding gene ChrX:100667936-100670552 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033281
 protein coding gene ChrX:95520875-95523348 (-)
CAST/EiJ MGP_CASTEiJ_G0034918
 protein coding gene ChrX:82471474-82474095 (-)
CBA/J MGP_CBAJ_G0035606
 protein coding gene ChrX:103783293-103785909 (-)
DBA/2J MGP_DBA2J_G0035760
 protein coding gene ChrX:96980388-96983004 (-)
FVB/NJ MGP_FVBNJ_G0035698
 protein coding gene ChrX:96364958-96367574 (-)
LP/J MGP_LPJ_G0035850
 protein coding gene ChrX:98723436-98726052 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035733
 protein coding gene ChrX:108333434-108336050 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036478
 protein coding gene ChrX:97453270-97455888 (-)
PWK/PhJ MGP_PWKPhJ_G0034617
 protein coding gene ChrX:80078700-80081425 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034445
 protein coding gene ChrX:83377341-83379961 (-)
WSB/EiJ MGP_WSBEiJ_G0035057
 protein coding gene ChrX:96158751-96161369 (-)



Homology
more
  • Human Ortholog
    CXorf65, chromosome X open reading frame 65
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CXorf65, chromosome X open reading frame 65
  • Links
    NCBI Gene ID: 158830
    neXtProt AC: NX_A6NEN9
    UniProt: A6NEN9

  • Chr Location
    Xq13.1; chrX:71103889-71106788 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 3 alleles in 3 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Germinal center B cell-specific homozygous knockout leads to protection from the autoimmune symptoms of experimentally-induced lupus because of increased B cell apoptosis. Overexpression leads to exacerbated symptoms because of suppressed apoptosis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000090141 Ensembl Gene Model | MGI Sequence Detail 2617 C57BL/6J ±  kb
transcript ENSMUST00000101358 Ensembl | MGI Sequence Detail 748 Not Applicable  
polypeptide ENSMUSP00000098910 Ensembl | MGI Sequence Detail 191 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory