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Mroh5 Gene Detail
Summary
  • Symbol
    Mroh5
  • Name
    maestro heat-like repeat family member 5
  • Synonyms
    Gm628, LOC268816
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685474
    NCBI Gene: 268816
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:73658785-73711520 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 34.06 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1515 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685474
 protein coding gene Chr15:73631916-73711548 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021925
 protein coding gene Chr15:73522281-73605169 (-)
A/J MGP_AJ_G0021884
 protein coding gene Chr15:70891057-70971373 (-)
AKR/J MGP_AKRJ_G0021866
 protein coding gene Chr15:72695784-72777363 (-)
BALB/cJ MGP_BALBcJ_G0021891
 protein coding gene Chr15:70896850-70975207 (-)
C3H/HeJ MGP_C3HHeJ_G0021664
 protein coding gene Chr15:72850785-72934503 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022331
 protein coding gene Chr15:76311875-76397876 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019867
 protein coding gene Chr15:67311033-67388726 (-)
CAST/EiJ MGP_CASTEiJ_G0021183
 protein coding gene Chr15:73651150-73738863 (-)
CBA/J MGP_CBAJ_G0021630
 protein coding gene Chr15:78804206-78887551 (-)
DBA/2J MGP_DBA2J_G0021755
 protein coding gene Chr15:70490110-70566866 (-)
FVB/NJ MGP_FVBNJ_G0021737
 protein coding gene Chr15:69512063-69590094 (-)
LP/J MGP_LPJ_G0021827
 protein coding gene Chr15:73542810-73632064 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021760
 protein coding gene Chr15:84157955-84240015 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022352
 protein coding gene Chr15:73090814-73167874 (-)
PWK/PhJ MGP_PWKPhJ_G0020924
 protein coding gene Chr15:70589479-70668293 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020765
 protein coding gene Chr15:72982668-73063839 (-)
WSB/EiJ MGP_WSBEiJ_G0021235
 protein coding gene Chr15:73094991-73175081 (-)



Homology
more
  • Human Ortholog
    MROH5, maestro heat like repeat family member 5 (gene/pseudogene)
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MROH5, maestro heat like repeat family member 5 (gene/pseudogene)
  • Links
    NCBI Gene ID: 389690
    neXtProt AC: NX_Q6ZUA9
    UniProt: Q6ZUA9

  • Chr Location
    8q24.3; chr8:141433825-141507230 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    28 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    5 involving Mroh5
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    41 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 268816 NCBI Gene Model | MGI Sequence Detail 52736 C57BL/6J ±  kb
transcript NM_001428951 RefSeq | MGI Sequence Detail 3962 C57BL/6  
polypeptide NP_001415880 RefSeq | MGI Sequence Detail 1293 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR011989 Armadillo-like helical
    IPR016024 Armadillo-type fold
    IPR045206 Maestro heat-like repeat-containing protein
    IPR048465 Maestro, HEAT repeats
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 8
References
more
  • Summaries
    All 42
    Diseases 1
    Gene Ontology 1
    Phenotypes 28
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory