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Ct45a Gene Detail
Summary
  • Symbol
    Ct45a
  • Name
    cancer/testis antigen 45
  • Synonyms
    Gm648, LOC270599
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685494
    NCBI Gene: 270599
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:55589234-55594966 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 30.06 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    252 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685494
 protein coding gene ChrX:55589233-55614583 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035737
 protein coding gene ChrX:51834327-51839864 (-)
A/J MGP_AJ_G0035720
 protein coding gene ChrX:52027545-52033277 (-)
AKR/J MGP_AKRJ_G0035640
 protein coding gene ChrX:53409318-53415052 (-)
BALB/cJ MGP_BALBcJ_G0035707
 protein coding gene ChrX:51496526-51502258 (-)
C3H/HeJ MGP_C3HHeJ_G0035409
 protein coding gene ChrX:52372153-52378030 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036236
 protein coding gene ChrX:53223996-53229886 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033087
 protein coding gene ChrX:51478985-51484789 (-)
CAST/EiJ MGP_CASTEiJ_G0034702
 protein coding gene ChrX:38261171-38266615 (-)
CBA/J MGP_CBAJ_G0035384
 protein coding gene ChrX:54769193-54778221 (-)
DBA/2J MGP_DBA2J_G0035538
 protein coding gene ChrX:51630699-51637071 (-)
FVB/NJ MGP_FVBNJ_G0035488
 protein coding gene ChrX:51231144-51236859 (-)
LP/J MGP_LPJ_G0035626
 protein coding gene ChrX:52429667-52435399 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035524
 protein coding gene ChrX:56309179-56314714 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036252
 protein coding gene ChrX:51869095-51874622 (-)
PWK/PhJ MGP_PWKPhJ_G0034398
 protein coding gene ChrX:36535748-36541696 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034242
 protein coding gene ChrX:38988554-38994169 (-)
WSB/EiJ MGP_WSBEiJ_G0034845
 protein coding gene ChrX:51403527-51411515 (-)



Homology
more
  • Human Ortholog
    CT45A1, cancer/testis antigen family 45 member A1
  • Vertebrate Orthologs
    10
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CT45A1, cancer/testis antigen family 45 member A1
  • Synonyms
    CT45, CT45-1, CT45.1
  • Links
    NCBI Gene ID: 541466
    neXtProt AC: NX_Q5HYN5
    UniProt: Q5HYN5

  • Chr Location
    Xq26.3; chrX:135708398-135723539 (+)  GRCh38
  • Human Ortholog
    CT45A10, cancer/testis antigen family 45 member A10
  • Synonyms
    CT45-5, CT45A5
  • Links
    NCBI Gene ID: 102723631
    neXtProt AC: NX_P0DMU8, NX_P0DMU9
    UniProt: P0DMU9

  • Chr Location
    chrX:135881063-135893444 (-)  GRCh38
  • Human Ortholog
    CT45A2, cancer/testis antigen family 45 member A2
  • Synonyms
    CT45-2, CT45.2, CT45A8, CT45A9
  • Links
    NCBI Gene ID: 728911
    neXtProt AC: NX_P0DMV1, NX_P0DMV2, NX_Q5DJT8
    UniProt: Q5DJT8

  • Chr Location
    Xq26.3; chrX:135811668-135820066 (-)  GRCh38
  • Human Ortholog
    CT45A3, cancer/testis antigen family 45 member A3
  • Synonyms
    CT45-3, CT45.3, CT45-4, CT45.4, CT45A4
  • Links
    NCBI Gene ID: 441519
    neXtProt AC: NX_Q8NHU0
    UniProt: Q8NHU0

  • Chr Location
    Xq26.3; chrX:135759846-135768191 (-)  GRCh38
  • Human Ortholog
    CT45A5, cancer/testis antigen family 45 member A5
  • Synonyms
    CT45-3, CT45-4, CT45.5, CT455, CT45-6, CT45A3, CT45A4, CT45A6, CT45A7
  • Links
    NCBI Gene ID: 441521
    neXtProt AC: NX_P0DMU7, NX_P0DMU8, NX_P0DMV0
    UniProt: P0DMU8

  • Chr Location
    Xq26.3; chrX:135775852-135785503 (-)  GRCh38
  • Human Ortholog
    CT45A6, cancer/testis antigen family 45 member A6
  • Synonyms
    CT45-5, CT45-6, CT45.6, CT45A5, CT45A7
  • Links
    NCBI Gene ID: 541465
    neXtProt AC: NX_P0DMU7, NX_P0DMU8, NX_P0DMV0
    UniProt: P0DMU7

  • Chr Location
    Xq26.3; chrX:135794685-135802787 (-)  GRCh38
  • Human Ortholog
    CT45A7, cancer/testis antigen family 45 member A7
  • Synonyms
    CT45-5, CT45-6, CT45A5, CT45A6
  • Links
    NCBI Gene ID: 101060211
    neXtProt AC: NX_P0DMU7, NX_P0DMU8, NX_P0DMV0
    UniProt: P0DMV0

  • Chr Location
    chrX:135829229-135837319 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000064016 Ensembl Gene Model | MGI Sequence Detail 5733 C57BL/6J ±  kb
    transcript ENSMUST00000081133 Ensembl | MGI Sequence Detail 1040 Not Applicable  
    polypeptide ENSMUSP00000079908 Ensembl | MGI Sequence Detail 213 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR051113 Integrator complex subunit 6
      IPR029307 INTS6/SAGE1/DDX26B/CT45, C-terminal
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 11

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:7444861
    References
    more
    • Summaries
      All 20
      Gene Ontology 1
      Phenotypes 5
    • Earliest
      J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory