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Clpsl2 Gene Detail
Summary
  • Symbol
    Clpsl2
  • Name
    colipase-like 2
  • Synonyms
    Gm749, LOC328788
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685595
    NCBI Gene: 328788
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:28768461-28771592 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 17, 14.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685595
protein coding gene Chr17:28768385-28771594 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023443
protein coding gene Chr17:27973133-27977440 (+)
A/J MGP_AJ_G0023401
protein coding gene Chr17:27033533-27036576 (+)
AKR/J MGP_AKRJ_G0023366
protein coding gene Chr17:27243556-27248224 (+)
BALB/cJ MGP_BALBcJ_G0023406
protein coding gene Chr17:27311068-27322002 (+)
C3H/HeJ MGP_C3HHeJ_G0023167
protein coding gene Chr17:27638548-27647250 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023848
protein coding gene Chr17:29097926-29104979 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021323
protein coding gene Chr17:24400136-24403784 (+)
CAST/EiJ MGP_CASTEiJ_G0022668
protein coding gene Chr17:27609127-27612107 (+)
CBA/J MGP_CBAJ_G0023141
protein coding gene Chr17:30148919-30154542 (+)
DBA/2J MGP_DBA2J_G0023272
protein coding gene Chr17:26592221-26596262 (+)
FVB/NJ MGP_FVBNJ_G0023242
protein coding gene Chr17:26406472-26415390 (+)
LP/J MGP_LPJ_G0023350
protein coding gene Chr17:28226830-28231230 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023260
protein coding gene Chr17:29558140-29562356 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023890
protein coding gene Chr17:27682127-27685233 (+)
PWK/PhJ MGP_PWKPhJ_G0022418
protein coding gene Chr17:25410118-25414136 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022236
protein coding gene Chr17:25662690-25669012 (+)
WSB/EiJ MGP_WSBEiJ_G0022730
protein coding gene Chr17:27672616-27677687 (+)



Homology
more
  • Human Ortholog
    CLPSL2, colipase like 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLPSL2, colipase like 2
  • Synonyms
    AAAL3045, C6orf126, dJ510O8.5, UNQ3045
  • Links
    NCBI Gene ID: 389383
    neXtProt AC: NX_Q6UWE3
    UniProt: Q6UWE3

  • Chr Location
    6p21.31

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice exhibit normal spermatozoa and fecundity.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 328788 NCBI Gene Model | MGI Sequence Detail 3132 C57BL/6J ±  kb
    transcript NM_001034871 RefSeq | MGI Sequence Detail 444 C57BL/6  
    polypeptide Q3UW21 UniProt | EBI | MGI Sequence Detail 102 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 1
    References
    more
    • Summaries
      All 26
      Gene Ontology 3
      Phenotypes 9
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:279041 Noda T, et al., Nine genes abundantly expressed in the epididymis are not essential for male fecundity in mice. Andrology. 2019;

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    11/12/2024
    MGI 6.24
    The Jackson Laboratory