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Ccdc78 Gene Detail
Summary
  • Symbol
    Ccdc78
  • Name
    coiled-coil domain containing 78
  • Synonyms
    LOC381077, LOC381146
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685784
    NCBI Gene: 381077
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:26005554-26009487 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 12.89 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    145 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685784
 protein coding gene Chr17:26005554-26009487 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023367
 protein coding gene Chr17:24882674-24886570 (+)
A/J MGP_AJ_G0023326
 protein coding gene Chr17:24159394-24163312 (+)
AKR/J MGP_AKRJ_G0023292
 protein coding gene Chr17:24263447-24269148 (+)
BALB/cJ MGP_BALBcJ_G0023331
 protein coding gene Chr17:24385029-24389350 (+)
C3H/HeJ MGP_C3HHeJ_G0023091
 protein coding gene Chr17:24646968-24650859 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023773
 protein coding gene Chr17:25935588-25939591 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021249
 protein coding gene Chr17:21620573-21624538 (+)
CAST/EiJ MGP_CASTEiJ_G0022593
 protein coding gene Chr17:24531082-24537993 (+)
CBA/J MGP_CBAJ_G0023066
 protein coding gene Chr17:26842933-26849795 (+)
DBA/2J MGP_DBA2J_G0023196
 protein coding gene Chr17:23759979-23763905 (+)
FVB/NJ MGP_FVBNJ_G0023166
 protein coding gene Chr17:23500633-23505200 (+)
LP/J MGP_LPJ_G0023273
 protein coding gene Chr17:25180404-25184315 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023185
 protein coding gene Chr17:26458670-26462579 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023813
 protein coding gene Chr17:24584307-24588253 (+)
PWK/PhJ MGP_PWKPhJ_G0022342
 protein coding gene Chr17:22522962-22526814 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022160
 protein coding gene Chr17:22656322-22660657 (+)
WSB/EiJ MGP_WSBEiJ_G0022656
 protein coding gene Chr17:24635241-24639170 (+)



Homology
more
  • Human Ortholog
    CCDC78, coiled-coil domain containing 78
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC78, coiled-coil domain containing 78
  • Synonyms
    C16orf25, CNM4, hsCCDC78, JFP10
  • Links
    NCBI Gene ID: 124093
    neXtProt AC: NX_A2IDD5
    UniProt: A2IDD5

  • Chr Location
    16p13.3
Human Diseases
more
  • Diseases
    1 with human CCDC78 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 381077 NCBI Gene Model | MGI Sequence Detail 3934 C57BL/6J ±  kb
    transcript NM_001165929 RefSeq | MGI Sequence Detail 1651 C57BL/6  
    polypeptide D3Z5T1 UniProt | EBI | MGI Sequence Detail 437 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000030377 coiled-coil domain-containing protein 78
      (term hierarchy)
    • InterPro Domains
      IPR039873 Coiled-coil domain-containing protein 78
      IPR029329 Domain of unknown function DUF4472
    • GlyGen
      D3Z5T1 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 7

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:2685796
    References
    more
    • Summaries
      All 29
      Gene Ontology 5
      Phenotypes 7
    • Earliest
      J:86784 Bergstrom DE, et al., Overlapping deletions spanning the proximal two-thirds of the mouse t complex. Mamm Genome. 2003 Dec;14(12):817-29
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory