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Sbk3 Gene Detail
Summary
  • Symbol
    Sbk3
  • Name
    SH3 domain binding kinase family, member 3
  • Synonyms
    Gm1078, LOC381835
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685924
    NCBI Gene: 381835
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr7:4968259-4974167 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.87 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    223 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685924
 protein coding gene Chr7:4968246-4995756 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031572
 protein coding gene Chr7:1918369-1924443 (-)
A/J MGP_AJ_G0031546
 protein coding gene Chr7:1925369-1931752 (-)
AKR/J MGP_AKRJ_G0031475
 protein coding gene Chr7:1999112-2004985 (-)
BALB/cJ MGP_BALBcJ_G0031554
 protein coding gene Chr7:1959947-1966021 (-)
C3H/HeJ MGP_C3HHeJ_G0031275
 protein coding gene Chr7:1979452-1985526 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032015
 protein coding gene Chr7:1988608-1994516 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029139
 protein coding gene Chr7:1644367-1650284 (-)
CAST/EiJ MGP_CASTEiJ_G0030639
 protein coding gene Chr7:1911692-1917555 (-)
CBA/J MGP_CBAJ_G0031233
 protein coding gene Chr7:2196071-2202145 (-)
DBA/2J MGP_DBA2J_G0031392
 protein coding gene Chr7:1895881-1901956 (-)
FVB/NJ MGP_FVBNJ_G0031344
 protein coding gene Chr7:1852316-1858390 (-)
LP/J MGP_LPJ_G0031477
 protein coding gene Chr7:2023451-2029525 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031383
 protein coding gene Chr7:2156590-2162665 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032045
 protein coding gene Chr7:1899449-1905361 (-)
PWK/PhJ MGP_PWKPhJ_G0030367
 protein coding gene Chr7:2062107-2068034 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030192
 protein coding gene Chr7:1944393-1950269 (-)
WSB/EiJ MGP_WSBEiJ_G0030734
 protein coding gene Chr7:1916774-1922678 (-)



Homology
more
  • Human Ortholog
    SBK3, SH3 domain binding kinase family member 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SBK3, SH3 domain binding kinase family member 3
  • Synonyms
    SGK110
  • Links
    NCBI Gene ID: 100130827
    neXtProt AC: NX_P0C264
    UniProt: P0C264

  • Chr Location
    19q13.42; chr19:55540656-55545543 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000085272 Ensembl Gene Model | MGI Sequence Detail 5909 C57BL/6J ±  kb
transcript ENSMUST00000133272 Ensembl | MGI Sequence Detail 1086 Not Applicable  
polypeptide ENSMUSP00000120654 Ensembl | MGI Sequence Detail 361 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Gene Ontology 5
    Phenotypes 1
  • Earliest
    J:91783 Caenepeel S, et al., The mouse kinome: discovery and comparative genomics of all mouse protein kinases. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11707-12
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory