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Lrcol1 Gene Detail
Summary
  • Symbol
    Lrcol1
  • Name
    leucine rich colipase-like 1
  • Synonyms
    Gm1679
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686525
    NCBI Gene: 381667
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:110492596-110503960 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 53.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    358 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686525
 protein coding gene Chr5:110492373-110503960 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029887
 protein coding gene Chr5:112792290-112803605 (+)
A/J MGP_AJ_G0029852
 protein coding gene Chr5:108426283-108438450 (+)
AKR/J MGP_AKRJ_G0029790
 protein coding gene Chr5:111881531-111894118 (+)
BALB/cJ MGP_BALBcJ_G0029863
 protein coding gene Chr5:109791448-109802948 (+)
C3H/HeJ MGP_C3HHeJ_G0029583
 protein coding gene Chr5:112300868-112313195 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030316
 protein coding gene Chr5:117241397-117252704 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027545
 protein coding gene Chr5:103253475-103264759 (+)
CAST/EiJ MGP_CASTEiJ_G0028991
 protein coding gene Chr5:111167304-111179246 (+)
CBA/J MGP_CBAJ_G0029550
 protein coding gene Chr5:121653617-121664822 (+)
DBA/2J MGP_DBA2J_G0029700
 protein coding gene Chr5:108490497-108501870 (+)
FVB/NJ MGP_FVBNJ_G0029657
 protein coding gene Chr5:107166235-107177367 (+)
LP/J MGP_LPJ_G0029788
 protein coding gene Chr5:113357536-113370847 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029688
 protein coding gene Chr5:126294811-126317529 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030357
 protein coding gene Chr5:111311582-111322915 (+)
PWK/PhJ MGP_PWKPhJ_G0028705
 protein coding gene Chr5:107080135-107090540 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028543
 protein coding gene Chr5:108772404-108783655 (+)
WSB/EiJ MGP_WSBEiJ_G0029067
 protein coding gene Chr5:111780817-111792287 (+)



Homology
more
  • Human Ortholog
    LRCOL1, leucine rich colipase like 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRCOL1, leucine rich colipase like 1
  • Links
    NCBI Gene ID: 100507055
    neXtProt AC: NX_A6NCL2
    UniProt: A6NCL2

  • Chr Location
    chr12:132603150-132610582 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Mice exhibit normal male fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000072754 Ensembl Gene Model | MGI Sequence Detail 11365 C57BL/6J ±  kb
    transcript ENSMUST00000185691 Ensembl | MGI Sequence Detail 764 Not Applicable  
    polypeptide ENSMUSP00000139397 Ensembl | MGI Sequence Detail 161 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 2
      cDNA 2

      Microarray probesets 2
    References
    more
    • Summaries
      All 25
      Gene Ontology 1
      Phenotypes 9
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:293870 Sun J, et al., CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction. Biol Reprod. 2020 Aug 4;103(2):183-194
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory