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Gene Expression Data
Assay Details
Assay
Reference: J:86704 Maynard TM, et al., A comprehensive analysis of 22q11 gene expression in the developing and adult brain. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14433-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3028322
Gene symbol: Cdc45
Gene name: cell division cycle 45
Antibody: CDC45L antiserum
Detection system: fluorescein
Assay notes: Specimens were fixed in 2.5% paraformaldehyde.
Results
Specimen 2h: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex Present Regionally restricted 2h Expression in subsets of neurons in multiple neocortical layers. Authors state that the frequency of labeled cells is diminished in layer 4.
Specimen 4 cerebellum: postnatal adult (more )
Note: Double labeled: green - Cdc45; red - Calb1 (assay MGI:5588111).
Structure Level Pattern Image Note
TS28: cerebellum Present 4_CDC45L Cerebellum Neuronal expression.
Specimen 4 hippocampus: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus pyramidal cell layer Present 4_CDC45L CA1 , 4_CDC45L CA3 Expression in pyramidal cells throughout all fields.
Specimen 4 dentate gyrus: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 4_CDC45L Dentate Gyrus
Specimen 4 striatum: postnatal adult (more )
Structure Level Pattern Image Note
TS28: basal ganglia Present Regionally restricted 4_CDC45L Striatum Expression in subsets of basal ganglia neurons.
TS28: corpus striatum Present 4_CDC45L Striatum No apparent specificity for any striatal compartment or cell class.
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Neuronal expression.
TS28: thalamus Present Neuronal expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
MGI 6.24 		The Jackson Laboratory