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Camsap1 Gene Detail
Summary
  • Symbol
    Camsap1
  • Name
    calmodulin regulated spectrin-associated protein 1
  • Synonyms
    9530003A05Rik, PRO2405
  • Feature Type
    protein coding gene
  • IDs
    MGI:3036242
    NCBI Gene: 227634
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:25816850-25873294 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 18.29 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1154 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3036242
 protein coding gene Chr2:25816850-25873574 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025475
 protein coding gene Chr2:23860327-23920771 (-)
A/J MGP_AJ_G0025452
 protein coding gene Chr2:22939736-22996599 (-)
AKR/J MGP_AKRJ_G0025422
 protein coding gene Chr2:23688520-23748591 (-)
BALB/cJ MGP_BALBcJ_G0025448
 protein coding gene Chr2:23049428-23105483 (-)
C3H/HeJ MGP_C3HHeJ_G0025209
 protein coding gene Chr2:23626860-23686216 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025892
 protein coding gene Chr2:24614470-24677908 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023303
 protein coding gene Chr2:21817895-21877211 (-)
CAST/EiJ MGP_CASTEiJ_G0024672
 protein coding gene Chr2:23508681-23570692 (-)
CBA/J MGP_CBAJ_G0025187
 protein coding gene Chr2:25453875-25523461 (-)
DBA/2J MGP_DBA2J_G0025320
 protein coding gene Chr2:22765237-22821363 (-)
FVB/NJ MGP_FVBNJ_G0025282
 protein coding gene Chr2:22518225-22572838 (-)
LP/J MGP_LPJ_G0025406
 protein coding gene Chr2:23794311-23857133 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025313
 protein coding gene Chr2:25631262-25696930 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025951
 protein coding gene Chr2:23645196-23706220 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0024220
 protein coding gene Chr2:23763458-23831257 (-)
WSB/EiJ MGP_WSBEiJ_G0024741
 protein coding gene Chr2:23719360-23806818 (-)



Homology
more
  • Human Ortholog
    CAMSAP1, calmodulin regulated spectrin associated protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CAMSAP1, calmodulin regulated spectrin associated protein 1
  • Synonyms
    CDCBM12
  • Links
    NCBI Gene ID: 157922
    neXtProt AC: NX_Q5T5Y3
    UniProt: Q5T5Y3

  • Chr Location
    9q34.3; chr9:135808487-135907546 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CAMSAP1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    758
  • Tissues
    22
  • cDNA Data
    13
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000026933 Ensembl Gene Model | MGI Sequence Detail 56445 C57BL/6J ±  kb
    transcript ENSMUST00000114167 Ensembl | MGI Sequence Detail 7981 Not Applicable  
    polypeptide ENSMUSP00000109804 Ensembl | MGI Sequence Detail 1582 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      9 Sequences
    • Protein Ontology
      PR:000004998 calmodulin-regulated spectrin-associated protein 1
      (term hierarchy)
    • InterPro Domains
      IPR032940 Calmodulin-regulated spectrin-associated protein
      IPR022613 Calmodulin-regulated spectrin-associated protein-like, Calponin-homology domain
      IPR001715 Calponin homology domain
      IPR031372 CAMSAP, spectrin and Ca2+/calmodulin-binding region
      IPR036872 CH domain superfamily
      IPR014797 CKK domain
      IPR038209 CKK domain superfamily
      IPR011033 PRC-barrel-like superfamily
    • GlyGen
      A2AHC3 2 sites, 1 O-linked glycan (2 sites)
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 13
      Primer pair 1

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:2139467
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 4
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory