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Ndufa4l2 Gene Detail
Summary
  • Symbol
    Ndufa4l2
  • Name
    Ndufa4, mitochondrial complex associated like 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3039567
    NCBI Gene: 407790
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:127350836-127353023 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 74.51 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    137 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3039567
 protein coding gene Chr10:127345143-127353023 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017824
 protein coding gene Chr10:131135123-131137336 (+)
A/J MGP_AJ_G0017799
 protein coding gene Chr10:125883298-125885510 (+)
AKR/J MGP_AKRJ_G0017762
 protein coding gene Chr10:129595611-129597824 (+)
BALB/cJ MGP_BALBcJ_G0017763
 protein coding gene Chr10:126285843-126288055 (+)
C3H/HeJ MGP_C3HHeJ_G0017587
 protein coding gene Chr10:129748896-129751138 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018218
 protein coding gene Chr10:135576184-135578397 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015898
 protein coding gene Chr10:119869614-119871794 (+)
CAST/EiJ MGP_CASTEiJ_G0017147
 protein coding gene Chr10:130407925-130410158 (+)
CBA/J MGP_CBAJ_G0017556
 protein coding gene Chr10:141044846-141047088 (+)
DBA/2J MGP_DBA2J_G0017662
 protein coding gene Chr10:124958366-124960613 (+)
FVB/NJ MGP_FVBNJ_G0017657
 protein coding gene Chr10:123897827-123900039 (+)
LP/J MGP_LPJ_G0017736
 protein coding gene Chr10:131705541-131707754 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017685
 protein coding gene Chr10:143740105-143742317 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018258
 protein coding gene Chr10:129664210-129666457 (+)
PWK/PhJ MGP_PWKPhJ_G0016932
 protein coding gene Chr10:125163952-125166218 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016724
 protein coding gene Chr10:128703067-128705270 (+)
WSB/EiJ MGP_WSBEiJ_G0017208
 protein coding gene Chr10:129890662-129892864 (+)



Homology
more
  • Human Ortholog
    NDUFA4L2, NDUFA4 mitochondrial complex associated like 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDUFA4L2, NDUFA4 mitochondrial complex associated like 2
  • Synonyms
    COXFA4L2, MISTRH, NUOMS
  • Links
    NCBI Gene ID: 56901
    neXtProt AC: NX_Q9NRX3
    UniProt: Q9NRX3

  • Chr Location
    12q13.3; chr12:57234903-57240762 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homzoygous for a conditional allele activated in carotid body glomus cells exhibit slightly higher responsiveness to hypoxia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    811
  • Tissues
    105
  • cDNA Data
    31
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040280 Ensembl Gene Model | MGI Sequence Detail 2188 C57BL/6J ±  kb
transcript ENSMUST00000035735 Ensembl | MGI Sequence Detail 934 Not Applicable  
polypeptide ENSMUSP00000042185 Ensembl | MGI Sequence Detail 87 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000011075 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2
    (term hierarchy)
  • InterPro Domains
    IPR010530 NADH-ubiquinone reductase complex 1 MLRQ subunit
Molecular
Reagents
less
  • All nucleic 34
    cDNA 31
    Primer pair 3

    Microarray probesets 2
References
more
  • Summaries
    All 33
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory