About   Help   FAQ
Slc22a27 Gene Detail
Summary
  • Symbol
    Slc22a27
  • Name
    solute carrier family 22, member 27
  • Synonyms
    AB056442, mOAT6 related protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:3042283
    NCBI Gene: 171405
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:7841753-7943392 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 5.36 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1957 from dbSNP Build 142
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3042283
 protein coding gene Chr19:7841753-7943899 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0024767
 protein coding gene Chr19:4684980-5143686 (-)
AKR/J MGP_AKRJ_G0024739
 protein coding gene Chr19:4780296-5217188 (-)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0024507
 protein coding gene Chr19:5462921-5728776 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0024600
 protein coding gene Chr19:4882776-5132009 (-)
LP/J MGP_LPJ_G0024720
 protein coding gene Chr19:4892721-4986966 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0025262
 protein coding gene Chr19:5218203-5342280 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SLC22A10, solute carrier family 22 member 10
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC22A10, solute carrier family 22 member 10
  • Synonyms
    hOAT5, OAT5
  • Links
    NCBI Gene ID: 387775
    neXtProt AC: NX_Q63ZE4
    UniProt: Q63ZE4

  • Chr Location
    11q12.3
  • Human Ortholog
    SLC22A25, solute carrier family 22 member 25
  • Synonyms
    HIMTP, UST6
  • Links
    NCBI Gene ID: 387601
    neXtProt AC: NX_Q6T423
    UniProt: Q6T423

  • Chr Location
    11q12.3; chr11:63158437-63243599 (-)  GRCh38
  • Human Ortholog
    SLC22A9, solute carrier family 22 member 9
  • Synonyms
    HOAT4, OAT4, OAT7, ust3, UST3H
  • Links
    NCBI Gene ID: 114571
    neXtProt AC: NX_Q8IVM8
    UniProt: Q8IVM8

  • Chr Location
    11q12.3; chr11:63369785-63410294 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human SLC22A9 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    730
  • Tissues
    12
  • cDNA Data
    2
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067656 Ensembl Gene Model | MGI Sequence Detail 101640 C57BL/6J ±  kb
transcript ENSMUST00000075619 Ensembl | MGI Sequence Detail 2152 Not Applicable  
polypeptide ENSMUSP00000093991 Ensembl | MGI Sequence Detail 551 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR005828 Major facilitator, sugar transporter-like
    IPR020846 Major facilitator superfamily domain
    IPR036259 MFS transporter superfamily
  • GlyGen
    Q76M72 5 sites
Molecular
Reagents
less
  • All nucleic 4
    cDNA 2
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 16
    Developmental Gene Expression 1
    Gene Ontology 4
  • Earliest
    J:157965 Wu W, et al., Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members. Physiol Genomics. 2009 Jul 9;38(2):116-24
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory