About   Help   FAQ
Lcn6 Gene Detail
Summary
  • Symbol
    Lcn6
  • Name
    lipocalin 6
  • Synonyms
    9230101D24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045364
    NCBI Gene: 620709
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:25566798-25571620 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 17.73 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    263 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045364
 protein coding gene Chr2:25566650-25571620 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025464
 protein coding gene Chr2:23590061-23594883 (+)
A/J MGP_AJ_G0025441
 protein coding gene Chr2:22670915-22675737 (+)
AKR/J MGP_AKRJ_G0025411
 protein coding gene Chr2:23429368-23434190 (+)
BALB/cJ MGP_BALBcJ_G0025437
 protein coding gene Chr2:22786197-22791019 (+)
C3H/HeJ MGP_C3HHeJ_G0025198
 protein coding gene Chr2:23365084-23369906 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025881
 protein coding gene Chr2:24345378-24350200 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023292
 protein coding gene Chr2:21577340-21582564 (+)
CAST/EiJ MGP_CASTEiJ_G0024661
 protein coding gene Chr2:23232612-23237433 (+)
CBA/J MGP_CBAJ_G0025176
 protein coding gene Chr2:25175960-25180782 (+)
DBA/2J MGP_DBA2J_G0025309
 protein coding gene Chr2:22515539-22520361 (+)
FVB/NJ MGP_FVBNJ_G0025271
 protein coding gene Chr2:22258157-22262979 (+)
LP/J MGP_LPJ_G0025395
 protein coding gene Chr2:23524432-23529254 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025302
 protein coding gene Chr2:25353576-25358398 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025940
 protein coding gene Chr2:23387893-23392723 (+)
PWK/PhJ MGP_PWKPhJ_G0024409
 protein coding gene Chr2:22324341-22329164 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024209
 protein coding gene Chr2:23522054-23527086 (+)
WSB/EiJ MGP_WSBEiJ_G0024730
 protein coding gene Chr2:23450368-23455198 (+)



Homology
more
  • Human Ortholog
    LCN6, lipocalin 6
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LCN6, lipocalin 6
  • Synonyms
    hLcn5, LCN5, UNQ643
  • Links
    NCBI Gene ID: 158062
    neXtProt AC: NX_P62502
    UniProt: P62502

  • Chr Location
    9q34.3
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice with loss of expression in the testes show premature acrosome reaction and elevated intracellular calcium levels in sperm.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045684 Ensembl Gene Model | MGI Sequence Detail 4823 C57BL/6J ±  kb
transcript ENSMUST00000114199 Ensembl | MGI Sequence Detail 729 Not Applicable  
polypeptide ENSMUSP00000109837 Ensembl | MGI Sequence Detail 181 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Phenotypes 7
  • Earliest
    J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
  • Latest
    J:340906 Sakurai N, et al., CRISPR/Cas9-mediated disruption of lipocalins, Ly6g5b, and Ly6g5c causes male subfertility in mice. Andrology. 2022 Nov 25;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory