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Adam39 Gene Detail
Summary
  • Symbol
    Adam39
  • Name
    a disintegrin and metallopeptidase domain 39
  • Synonyms
    1700056P18Rik, testase 9
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045694
    NCBI Gene: 546055
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:41276046-41279898 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 23.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    185 from dbSNP Build 142
  • Strain Annotations
    3
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045694
 protein coding gene Chr8:41276027-41280074 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0033538
 protein coding gene Chr8:38140272-38143419 (+)
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0030998
 protein coding gene Chr8:34807652-34811607 (+)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ADAM20, ADAM metallopeptidase domain 20
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ADAM20, ADAM metallopeptidase domain 20
  • Links
    NCBI Gene ID: 8748
    neXtProt AC: NX_O43506
    UniProt: O43506

  • Chr Location
    14q24.2; chr14:70522358-70579452 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 546055 NCBI Gene Model | MGI Sequence Detail 3853 C57BL/6J ±  kb
transcript NM_001025380 RefSeq | MGI Sequence Detail 2441 Not Specified  
polypeptide NP_001020551 RefSeq | MGI Sequence Detail 756 Not Specified  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 2
References
more
  • Summaries
    All 17
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:84749 Puente XS, et al., Human and mouse proteases: a comparative genomic approach. Nat Rev Genet. 2003 Jul;4(7):544-58
  • Latest
    J:348447 Nguyen TTT, et al., Gene-deficient mouse model established by CRISPR/Cas9 system reveals 15 reproductive organ-enriched genes dispensable for male fertility. Frontiers in Cell and Developmental Biology. 2024;12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory