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Ggnbp1 Gene Detail
Summary
  • Symbol
    Ggnbp1
  • Name
    gametogenetin binding protein 1
  • Synonyms
    0610031G08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3055306
    NCBI Gene: 70772
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:27237009-27255352 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 13.60 cM, cytoband B1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    631 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3055306
 protein coding gene Chr17:27236961-27256598 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023414
 protein coding gene Chr17:26204395-26277760 (+)
A/J MGP_AJ_G0023371
 protein coding gene Chr17:25404646-25470629 (+)
AKR/J MGP_AKRJ_G0023337
 protein coding gene Chr17:25538565-25607553 (+)
BALB/cJ MGP_BALBcJ_G0023376
 protein coding gene Chr17:25647637-25720586 (+)
C3H/HeJ MGP_C3HHeJ_G0023137
 protein coding gene Chr17:25913991-25988088 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023819
 protein coding gene Chr17:27307936-27383064 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021293
 protein coding gene Chr17:22814291-22884533 (+)
CAST/EiJ MGP_CASTEiJ_G0022638
 protein coding gene Chr17:25842420-25912736 (+)
CBA/J MGP_CBAJ_G0023111
 protein coding gene Chr17:28258283-28333081 (+)
DBA/2J MGP_DBA2J_G0023243
 protein coding gene Chr17:24966843-25033298 (+)
FVB/NJ MGP_FVBNJ_G0023212
 protein coding gene Chr17:24752522-24817398 (+)
LP/J MGP_LPJ_G0023320
 protein coding gene Chr17:26453137-26523063 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023230
 protein coding gene Chr17:27778638-27855672 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023860
 protein coding gene Chr17:25910355-25981878 (+)
PWK/PhJ MGP_PWKPhJ_G0022388
 protein coding gene Chr17:23765151-23833780 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022206
 protein coding gene Chr17:23948515-24018683 (+)
WSB/EiJ MGP_WSBEiJ_G0022701
 protein coding gene Chr17:25934692-26008780 (+)



Homology
more
  • Human Ortholog
    GGNBP1, gametogenetin binding protein 1 (pseudogene)
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GGNBP1, gametogenetin binding protein 1 (pseudogene)
  • Links
    NCBI Gene ID: 449520
    UniProt: Q5YKI7

  • Chr Location
    6p21.31; chr6:33540046-33589026 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit male infertility, asthenozoospermia, and teratozoospermia in a portion of mice and increased sensitivity to BPA-induced sperm damage.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    4
  • cDNA Data
    8
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 70772 NCBI Gene Model | MGI Sequence Detail 18344 C57BL/6J ±  kb
    transcript NM_027544 RefSeq | MGI Sequence Detail 1525 C57BL/6  
    polypeptide Q6K1E7 UniProt | EBI | MGI Sequence Detail 370 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1922643
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:351297 Ge T, et al., Coiled-coil domain containing 159 is required for spermatid head and tail assembly in mice. Biol Reprod. 2024 May 9;110(5):877-894
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory