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Stfa2l1 Gene Detail
Summary
  • Symbol
    Stfa2l1
  • Name
    stefin A2 like 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3524944
    NCBI Gene: 268885
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:35977181-35982318 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 25.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    248 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3524944
 protein coding gene Chr16:35977181-35982323 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022781
 protein coding gene Chr16:34529985-34537218 (+)
A/J MGP_AJ_G0022746
 protein coding gene Chr16:32855109-32860450 (+)
AKR/J MGP_AKRJ_G0022718
 protein coding gene Chr16:34009250-34013543 (+)
BALB/cJ MGP_BALBcJ_G0022753
 protein coding gene Chr16:33188692-33193409 (-)
C3H/HeJ MGP_C3HHeJ_G0022512
 protein coding gene Chr16:34130968-34136524 (+)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0022044
 protein coding gene Chr16:34493635-34494338 (-)
CBA/J MGP_CBAJ_G0022488
 protein coding gene Chr16:37160780-37175471 (-)
DBA/2J MGP_DBA2J_G0022615
 protein coding gene Chr16:32677106-32684246 (+)
FVB/NJ MGP_FVBNJ_G0022591
 protein coding gene Chr16:32670317-32675322 (+)
LP/J MGP_LPJ_G0022682
 protein coding gene Chr16:34254229-34258903 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022610
 protein coding gene Chr16:35994835-36003112 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023209
 protein coding gene Chr16:34070364-34078653 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0021613
 protein coding gene Chr16:33870422-33877984 (+)
WSB/EiJ MGP_WSBEiJ_G0022085
 protein coding gene Chr16:33987404-33988221 (+)



Homology
more
  • Human Ortholog
    CSTA, cystatin A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CSTA, cystatin A
  • Synonyms
    AREI, PSS4, STF1, STFA
  • Links
    NCBI Gene ID: 1475
    neXtProt AC: NX_P01040
    UniProt: P01040

  • Chr Location
    3q21.1; chr3:122325248-122341969 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CSTA associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 268885 NCBI Gene Model | MGI Sequence Detail 5138 C57BL/6J ±  kb
transcript NM_173869 RefSeq | MGI Sequence Detail 414 C57BL/6  
polypeptide NP_776294 RefSeq | MGI Sequence Detail 103 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR000010 Cystatin domain
    IPR046350 Cystatin superfamily
    IPR001713 Proteinase inhibitor I25A, stefin
    IPR018073 Proteinase inhibitor I25, cystatin, conserved site
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 14
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:154850 Bilodeau M, et al., A retroviral strategy that efficiently creates chromosomal deletions in mammalian cells. Nat Methods. 2007 Mar;4(3):263-8
  • Latest
    J:154051 Bilodeau M, et al., Analysis of blood stem cell activity and cystatin gene expression in a mouse model presenting a chromosomal deletion encompassing Csta and Stfa2l1. PLoS One. 2009;4(10):e7500
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory