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Gene Expression Data
Assay Details
Assay
Reference: J:96323 Hirai S, et al., Expression of MUK/DLK/ZPK, an activator of the JNK pathway, in the nervous systems of the developing mouse embryo. Gene Expr Patterns. 2005 Apr;5(4):517-23
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3581158
Gene symbol: Map3k12
Gene name: mitogen-activated protein kinase kinase kinase 12
Antibody: anti-MUK
Detection system: Secondary antibody coupled to alkaline phosphatase
Results
Specimen 1A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: future forebrain Absent 1A
Specimen 1B: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: future hindbrain Present Regionally restricted 1B Expression is in the junctional region between the midbrain and hindbrain.
TS16: future midbrain Present Regionally restricted 1B Expression is in the junctional region between the midbrain and hindbrain.
Specimen 1C: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: dorsal root ganglion Weak 1C
Specimen 1G: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: future hindbrain Present Regionally restricted 1G Expression is in the junctional region between the midbrain and hindbrain.
TS16: future midbrain Present Regionally restricted 1G Expression is in the junctional region between the midbrain and hindbrain.
Specimen 1H: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: dorsal root ganglion Weak 1H
Specimen 2A: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: brain Present 2A
TS18: central nervous system ganglion Present 2A
TS18: dorsal root ganglion Present 2A
TS18: future spinal cord Present 2A
TS18: liver Present 2A
TS18: sympathetic ganglion Present 2A
TS18: telencephalon Present Regionally restricted 2A Expression is absent in neocortical region.
Specimen 2B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: brain Present 2B
TS18: central nervous system ganglion Present 2B
TS18: dorsal root ganglion Present 2B
TS18: future spinal cord Present 2B
TS18: sympathetic ganglion Present 2B
TS18: telencephalon Present Regionally restricted 2B Expression is absent in neocortical region.
Specimen 2C: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: central nervous system ganglion Present 2C
TS18: diencephalon lateral wall marginal layer Present 2C
TS18: dorsal root ganglion Present 2C
TS18: midbrain marginal layer Present 2C
TS18: neural tube marginal layer Present 2C
TS18: sympathetic ganglion Present 2C
TS18: hindbrain lateral wall Present Regionally restricted 2C Expression is in the marginal zone.
TS18: telencephalon Present Regionally restricted 2C Expression is absent in neocortical region.
Specimen 3A: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: central nervous system Present 3A
TS22: cranial ganglion Present 3A
TS22: dorsal root ganglion Present 3A
TS22: glossopharyngeal ganglion Present 3A
TS22: inferior cervical ganglion Present 3A
TS22: parasympathetic nervous system Present 3A
TS22: peripheral nerve trunk Present 3A
TS22: peripheral nervous system Present 3A
TS22: superior cervical ganglion Present 3A
TS22: sympathetic nervous system Present 3A
TS22: trigeminal ganglion Present 3A
TS22: vagal nerve trunk Present 3A
TS22: vestibulo-cochlear ganglion Present 3A
TS22: liver Absent 3A
Specimen 3B: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: central nervous system Present 3B
TS22: cranial ganglion Present 3B
TS22: dorsal root ganglion Present 3B
TS22: glossopharyngeal ganglion Present 3B
TS22: inferior cervical ganglion Present 3B
TS22: parasympathetic nervous system Present 3B
TS22: peripheral nerve trunk Present 3B
TS22: peripheral nervous system Present 3B
TS22: superior cervical ganglion Present 3B
TS22: sympathetic nervous system Present 3B
TS22: trigeminal ganglion Present 3B
TS22: vagal nerve trunk Present 3B
TS22: vestibulo-cochlear ganglion Present 3B
TS22: liver Absent 3B
TS22: cerebral cortex ventricular layer Absent 3B Absent in undifferentiated neural precursors.
Specimen 3C: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: central nervous system Present 3C
TS22: cranial ganglion Present 3C
TS22: dorsal root ganglion Present 3C
TS22: glossopharyngeal ganglion Present 3C
TS22: inferior cervical ganglion Present 3C
TS22: parasympathetic nervous system Present 3C
TS22: peripheral nerve trunk Present 3C
TS22: peripheral nervous system Present 3C
TS22: superior cervical ganglion Present 3C
TS22: sympathetic nervous system Present 3C
TS22: trigeminal ganglion Present 3C
TS22: vagal nerve trunk Present 3C
TS22: vestibulo-cochlear ganglion Present 3C
TS22: liver Absent 3C
Specimen 3G: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: peripheral nervous system Present 3G
Specimen 4A: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: inferior glossopharyngeal ganglion Present 4A
TS22: inferior vagus ganglion Present 4A
TS22: superior vagus ganglion Present 4A
TS22: trigeminal ganglion Present 4A
TS22: vestibulo-cochlear ganglion Present 4A
Specimen 4B: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: glossopharyngeal nerve Present 4B
Specimen 4C: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: cranial ganglion Present 4C
Specimen 6A: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: brain Present 6A Neural tracts and reticular formations had stronger staining.
TS24: retina nuclear layer Present 6A
Specimen 6F: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: spinal cord marginal layer Present 6F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory