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Degs1l Gene Detail
Summary
  • Symbol
    Degs1l
  • Name
    delta 4-desaturase, sphingolipid 1 like
  • Synonyms
    9130409I23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3588271
    NCBI Gene: 619326
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:180878802-180888232 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 84.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    323 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3588271
 protein coding gene Chr1:180863166-180888326 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016881
 protein coding gene Chr1:187541077-187550498 (+)
A/J MGP_AJ_G0016860
 protein coding gene Chr1:179950419-179959824 (+)
AKR/J MGP_AKRJ_G0016826
 protein coding gene Chr1:185291382-185300746 (+)
BALB/cJ MGP_BALBcJ_G0016818
 protein coding gene Chr1:180585625-180595066 (+)
C3H/HeJ MGP_C3HHeJ_G0016643
 protein coding gene Chr1:186078462-186088545 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017281
 protein coding gene Chr1:193635024-193644450 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0016224
 protein coding gene Chr1:185422775-185432147 (+)
CBA/J MGP_CBAJ_G0016617
 protein coding gene Chr1:200764989-200774384 (+)
DBA/2J MGP_DBA2J_G0016723
 protein coding gene Chr1:178777746-178787402 (+)
FVB/NJ MGP_FVBNJ_G0016719
 protein coding gene Chr1:176876967-176886370 (+)
LP/J MGP_LPJ_G0016797
 protein coding gene Chr1:188792783-188802195 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016750
 protein coding gene Chr1:207924998-207934467 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017318
 protein coding gene Chr1:185072962-185082334 (+)
PWK/PhJ MGP_PWKPhJ_G0016012
 protein coding gene Chr1:177897893-177907428 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015788
 protein coding gene Chr1:184038656-184047841 (+)
WSB/EiJ MGP_WSBEiJ_G0016287
 protein coding gene Chr1:185279745-185289985 (+)



Homology
more
  • Human Ortholog
    DEGS1, delta 4-desaturase, sphingolipid 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DEGS1, delta 4-desaturase, sphingolipid 1
  • Synonyms
    DEGS, DEGS-1, Des-1, DES1, FADS7, HLD18, MIG15, MLD
  • Links
    NCBI Gene ID: 8560
    neXtProt AC: NX_O15121
    UniProt: O15121

  • Chr Location
    1q42.11; chr1:224175756-224193441 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human DEGS1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038768 Ensembl Gene Model | MGI Sequence Detail 9431 C57BL/6J ±  kb
transcript ENSMUST00000036819 Ensembl | MGI Sequence Detail 1898 Not Applicable  
polypeptide ENSMUSP00000042889 Ensembl | MGI Sequence Detail 320 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 3
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:7414179
References
more
  • Summaries
    All 18
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory