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Acaa1b Gene Detail
Summary
  • Symbol
    Acaa1b
  • Name
    acetyl-Coenzyme A acyltransferase 1B
  • Synonyms
    thiolase B
  • Feature Type
    protein coding gene
  • IDs
    MGI:3605455
    NCBI Gene: 235674
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:118977111-118986149 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 71.33 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    341 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3605455
 protein coding gene Chr9:118977091-118986161 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035412
 protein coding gene Chr9:121861695-121878481 (-)
A/J MGP_AJ_G0035392
 protein coding gene Chr9:117364552-117374031 (-)
AKR/J MGP_AKRJ_G0035325
 protein coding gene Chr9:120401300-120414709 (-)
BALB/cJ MGP_BALBcJ_G0035388
 protein coding gene Chr9:117233741-117243697 (-)
C3H/HeJ MGP_C3HHeJ_G0035096
 protein coding gene Chr9:120871597-120884855 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035911
 protein coding gene Chr9:125209583-125227888 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032794
 protein coding gene Chr9:114556370-114565737 (-)
CAST/EiJ MGP_CASTEiJ_G0034400
 protein coding gene Chr9:120840794-120848950 (-)
CBA/J MGP_CBAJ_G0035063
 protein coding gene Chr9:129918412-129927257 (-)
DBA/2J MGP_DBA2J_G0035222
 protein coding gene Chr9:116802082-116812619 (-)
FVB/NJ MGP_FVBNJ_G0035169
 protein coding gene Chr9:115646926-115656105 (-)
LP/J MGP_LPJ_G0035301
 protein coding gene Chr9:122214284-122227171 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035210
 protein coding gene Chr9:130902034-130910324 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035930
 protein coding gene Chr9:120791571-120802746 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0033941
 protein coding gene Chr9:120904787-120920313 (-)
WSB/EiJ MGP_WSBEiJ_G0034521
 protein coding gene Chr9:120680440-120687835 (-)



Homology
more
  • Human Ortholog
    ACAA1, acetyl-CoA acyltransferase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACAA1, acetyl-CoA acyltransferase 1
  • Synonyms
    ACAA, Lnc-Myd88, PTHIO, THIO
  • Links
    NCBI Gene ID: 30
    neXtProt AC: NX_P09110
    UniProt: P09110

  • Chr Location
    3p22.2; chr3:38103129-38137242 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Mice homozygous for a disruption in this gene appear normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1023
  • Tissues
    230
  • cDNA Data
    131
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 235674 NCBI Gene Model | MGI Sequence Detail 9039 C57BL/6J ±  kb
transcript NM_146230 RefSeq | MGI Sequence Detail 1642 C57BL/6  
polypeptide Q8VCH0 UniProt | EBI | MGI Sequence Detail 424 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 132
    cDNA 131
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 40
    Developmental Gene Expression 6
    Gene Ontology 8
    Phenotypes 13
  • Earliest
    J:12215 Chubb C, Oligotriche and quaking gene mutations. Phenotypic effects on mouse spermatogenesis and testicular steroidogenesis. J Androl. 1992 Jul-Aug;13(4):312-7
  • Latest
    J:281596 Man JCK, et al., An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo. Nat Commun. 2019 Oct 30;10(1):4943
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory