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Mir135a-2 Gene Detail
Summary
  • Symbol
    Mir135a-2
  • Name
    microRNA 135a-2
  • Synonyms
    mir 135a-2, Mirn135a-2, mmu-mir-135a-2
  • Feature Type
    miRNA gene
  • IDs
    MGI:3618729
    NCBI Gene: 723955
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:91907948-91908047 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 46.67 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    91 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3618729
 miRNA gene Chr10:91907948-91908047 (-)
129S1/SvImJ MGP_129S1SvImJ_G0007741
 miRNA gene Chr10:93404447-93404546 (-)
A/J MGP_AJ_G0007737
 miRNA gene Chr10:90174988-90175087 (-)
AKR/J MGP_AKRJ_G0007712
 miRNA gene Chr10:92729621-92729720 (-)
BALB/cJ MGP_BALBcJ_G0007715
 miRNA gene Chr10:90449886-90449985 (-)
C3H/HeJ MGP_C3HHeJ_G0007661
 miRNA gene Chr10:92757564-92757663 (-)
C57BL/6NJ MGP_C57BL6NJ_G0007891
 miRNA gene Chr10:96488283-96488382 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0007048
 miRNA gene Chr10:85802628-85802727 (-)
CAST/EiJ MGP_CASTEiJ_G0007556
 miRNA gene Chr10:92692450-92692549 (-)
CBA/J MGP_CBAJ_G0007634
 miRNA gene Chr10:100476958-100477057 (-)
DBA/2J MGP_DBA2J_G0007668
 miRNA gene Chr10:89285976-89286075 (-)
FVB/NJ MGP_FVBNJ_G0007685
 miRNA gene Chr10:88499923-88500022 (-)
LP/J MGP_LPJ_G0007746
 miRNA gene Chr10:94023234-94023333 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0007658
 miRNA gene Chr10:101878759-101878858 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0007889
 miRNA gene Chr10:92646989-92647088 (-)
PWK/PhJ MGP_PWKPhJ_G0007488
 miRNA gene Chr10:89339753-89339852 (-)
SPRET/EiJ MGP_SPRETEiJ_G0007385
 miRNA gene Chr10:91405431-91405530 (-)
WSB/EiJ MGP_WSBEiJ_G0007623
 miRNA gene Chr10:92610251-92610350 (-)



Homology
more
  • Human Ortholog
    MIR135A2, microRNA 135a-2
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR135A2, microRNA 135a-2
  • Synonyms
    mir-135a-2, MIRN135-2, MIRN135A2
  • Links
    NCBI Gene ID: 406926

  • Chr Location
    chr12:97563812-97563911 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Targeted
    1
  • Transposon induced
    1
  • Genomic Mutations
    2 involving Mir135a-2
  • Find Mice (IMSR)
    0 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    768
  • Tissues
    39
  • Literature Summary
    11
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 723955 NCBI Gene Model | MGI Sequence Detail 100 C57BL/6J ±  kb
transcript NR_029812 RefSeq | MGI Sequence Detail 100 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 8
    Primer pair 5
    Other 3
Other Database
Links
less
miRBase MI0000715
References
more
  • Summaries
    All 34
    Developmental Gene Expression 11
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:289958 Shen S, et al., Silencing of GAS5 represses the malignant progression of atherosclerosis through upregulation of miR-135a. Biomed Pharmacother. 2019 Oct;118:109302
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory