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Mir448 Gene Detail
Summary
  • Symbol
    Mir448
  • Name
    microRNA 448
  • Synonyms
    mir 448, mir-448, Mirn448, mmu-mir-448
  • Feature Type
    miRNA gene
  • IDs
    MGI:3619406
    NCBI Gene: 723914
  • Alliance
Location &
Maps
more
  • Sequence Map
    ChrX:145941206-145941317 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 68.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    61 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3619406
miRNA gene ChrX:145941206-145941317 (+)
129S1/SvImJ MGP_129S1SvImJ_G0009359
miRNA gene ChrX:144772657-144772768 (+)
A/J MGP_AJ_G0009341
miRNA gene ChrX:144033857-144033968 (+)
AKR/J MGP_AKRJ_G0009329
miRNA gene ChrX:148776290-148776401 (+)
BALB/cJ MGP_BALBcJ_G0009323
miRNA gene ChrX:142263711-142263822 (+)
C3H/HeJ MGP_C3HHeJ_G0009263
miRNA gene ChrX:144879028-144879139 (+)
C57BL/6NJ MGP_C57BL6NJ_G0009569
miRNA gene ChrX:148866187-148866298 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0008402
miRNA gene ChrX:135501144-135501255 (+)
CAST/EiJ MGP_CASTEiJ_G0009089
miRNA gene ChrX:125420312-125420423 (+)
CBA/J MGP_CBAJ_G0009233
miRNA gene ChrX:153482636-153482747 (+)
DBA/2J MGP_DBA2J_G0009260
miRNA gene ChrX:143087702-143087813 (+)
FVB/NJ MGP_FVBNJ_G0009279
miRNA gene ChrX:142312403-142312514 (+)
LP/J MGP_LPJ_G0009356
miRNA gene ChrX:145661399-145661510 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0009245
miRNA gene ChrX:161573322-161573433 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0009536
miRNA gene ChrX:144038628-144038739 (+)
PWK/PhJ MGP_PWKPhJ_G0009014
miRNA gene ChrX:122138058-122138169 (+)
SPRET/EiJ MGP_SPRETEiJ_G0008855
miRNA gene ChrX:125983682-125983793 (+)
WSB/EiJ MGP_WSBEiJ_G0009188
miRNA gene ChrX:142350063-142350174 (+)



Homology
more
  • Human Ortholog
    MIR448, microRNA 448
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR448, microRNA 448
  • Synonyms
    hsa-mir-448, MIRN448, miRNA448
  • Links
    NCBI Gene ID: 554212

  • Chr Location
    chrX:114823454-114823564 (+)  GRCh38

Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 723914 NCBI Gene Model | MGI Sequence Detail 112 C57BL/6J ±  kb
transcript NR_029956 RefSeq | MGI Sequence Detail 112 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 1
    Other 1
Other Database
Links
less
miRBase MI0001638
References
more
  • Summaries
    All 11
    Developmental Gene Expression 2
    Gene Ontology 1
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:295820 Lv CL, et al., MicroRNA-448 inhibits the regeneration of spinal cord injury through PI3K/AKT/Bcl-2 axis. Eur Rev Med Pharmacol Sci. 2019 Apr;23(7):2719-2726

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory