About   Help   FAQ
Igkv8-30 Gene Detail
Summary
  • Symbol
    Igkv8-30
  • Name
    immunoglobulin kappa chain variable 8-30
  • Synonyms
    ENSMUSG00000073025, Gm10883
  • Feature Type
    gene segment
  • IDs
    MGI:3642250
    NCBI Gene: 384419
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:70094045-70094601 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 31.76 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    184 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3642250
 gene segment Chr6:70094045-70094604 (-)
129S1/SvImJ MGP_129S1SvImJ_G0000167
 gene segment Chr6:70464584-70465143 (-)
A/J MGP_AJ_G0000148
 gene segment Chr6:67672109-67672668 (-)
AKR/J MGP_AKRJ_G0000148
 gene segment Chr6:69672213-69672773 (-)
BALB/cJ MGP_BALBcJ_G0000141
 gene segment Chr6:67831585-67832144 (-)
C3H/HeJ MGP_C3HHeJ_G0000108
 gene segment Chr6:114592563-114593122 (+)
C57BL/6NJ MGP_C57BL6NJ_G0000205
 gene segment Chr6:72254697-72255256 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0000153
 gene segment Chr6:69561087-69561647 (-)
CBA/J no annotation
DBA/2J MGP_DBA2J_G0000141
 gene segment Chr6:67107175-67107734 (-)
FVB/NJ MGP_FVBNJ_G0000139
 gene segment Chr6:66531538-66532097 (-)
LP/J MGP_LPJ_G0000170
 gene segment Chr6:70296868-70297427 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0000187
 gene segment Chr6:69566028-69566587 (-)
PWK/PhJ MGP_PWKPhJ_G0000128
 gene segment Chr6:66136366-66136926 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IGKV4-1, immunoglobulin kappa variable 4-1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGKV4-1, immunoglobulin kappa variable 4-1
  • Synonyms
    B3, IGKV41
  • Links
    NCBI Gene ID: 28908
    UniProt: P06312

  • Chr Location
    2p11.2; chr2:88885397-88886153 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
  • UniProt
    3
Representative SequencesLengthStrain/SpeciesFlank
genomic 384419 NCBI Gene Model | MGI Sequence Detail 557 C57BL/6J ±  kb
transcript BC094049 GenBank | ENA | DDBJ | MGI Sequence Detail 1002 C57BL/6  
polypeptide Q52L64 UniProt | EBI | MGI Sequence Detail 240 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 2
References
more
  • Summaries
    All 11
    Gene Ontology 1
  • Earliest
    J:720 Kofler H, et al., Mechanism of allergic cross-reactions--III. cDNA cloning and variable-region sequence analysis of two IgE antibodies specific for trinitrophenyl. Mol Immunol. 1992 Feb;29(2):161-6
  • Latest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory