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Iglc4 Pseudogene Detail
Summary
  • Symbol
    Iglc4
  • Name
    immunoglobulin lambda constant 4
Location &
Maps
more
  • Sequence Map
    Chr16:19013749-19014062 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 11.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    79 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3642936
 pseudogenic gene segment Chr16:19013749-19014062 (-)
129S1/SvImJ MGP_129S1SvImJ_G0000013
 gene segment Chr16:16475491-16475804 (-)
A/J MGP_AJ_G0000013
 gene segment Chr16:15652498-15652811 (-)
AKR/J MGP_AKRJ_G0000012
 gene segment Chr16:16281715-16282028 (-)
BALB/cJ MGP_BALBcJ_G0000013
 gene segment Chr16:15817359-15817672 (-)
C3H/HeJ MGP_C3HHeJ_G0000013
 gene segment Chr16:16444659-16444972 (-)
C57BL/6NJ MGP_C57BL6NJ_G0000013
 gene segment Chr16:16776270-16776583 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0000011
 gene segment Chr16:15688294-15688613 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0000013
 gene segment Chr16:17512677-17512990 (-)
DBA/2J MGP_DBA2J_G0000013
 gene segment Chr16:15549572-15549885 (-)
FVB/NJ MGP_FVBNJ_G0000013
 gene segment Chr16:15636074-15636387 (-)
LP/J MGP_LPJ_G0000013
 gene segment Chr16:16220225-16220538 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0000012
 gene segment Chr16:17123941-17124254 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0000013
 gene segment Chr16:16198709-16199022 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0000011
 gene segment Chr16:16088180-16088493 (-)
WSB/EiJ MGP_WSBEiJ_G0000013
 gene segment Chr16:16233639-16233952 (-)



Homology
more
  • Human Ortholog
    IGLC2, immunoglobulin lambda constant 2
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGLC2, immunoglobulin lambda constant 2
  • Synonyms
    IGLC
  • Links
    NCBI Gene ID: 3538
    UniProt: P0DOY2

  • Chr Location
    22q11.22; chr22:22900976-22901437 (+)  GRCh38
  • Human Ortholog
    IGLC3, immunoglobulin lambda constant 3 (Kern-Oz+ marker)
  • Synonyms
    IGLC
  • Links
    NCBI Gene ID: 3539
    UniProt: P0DOY3

  • Chr Location
    22q11.22; chr22:22906342-22906803 (+)  GRCh38
  • Human Ortholog
    IGLC6, immunoglobulin lambda constant 6
  • Synonyms
    IGLC
  • Links
    NCBI Gene ID: 3542
    UniProt: P0CF74

  • Chr Location
    22q11.22; chr22:22919535-22919858 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    22
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 404736 NCBI Gene Model | MGI Sequence Detail 314 C57BL/6J ±  kb
polypeptide A0A0G2JEK5 UniProt | EBI | MGI Sequence Detail 104 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR050160 Major Histocompatibility Complex/Immunoglobulin
References
more
  • Summaries
    All 12
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:20109 Weiss S, et al., Somatic point mutations in unrearranged immunoglobulin gene segments encoding the variable region of lambda light chains. EMBO J. 1987 Apr;6(4):927-32
  • Latest
    J:151668 Matheson LS, et al., Light chain-deficient mice produce novel multimeric heavy-chain-only IgA by faulty class switching. Int Immunol. 2009 Aug;21(8):957-66
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory