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Defb26 Gene Detail
Summary
  • Symbol
    Defb26
  • Name
    defensin beta 26
  • Synonyms
    EG654457
  • Feature Type
    protein coding gene
  • IDs
    MGI:3643488
    NCBI Gene: 654457
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:152349718-152353612 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 75.18 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    157 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3643488
 protein coding gene Chr2:152349490-152353662 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026664
 protein coding gene Chr2:157070491-157074259 (-)
A/J MGP_AJ_G0026630
 protein coding gene Chr2:150795762-150799613 (-)
AKR/J MGP_AKRJ_G0026600
 protein coding gene Chr2:155202157-155205949 (-)
BALB/cJ MGP_BALBcJ_G0026639
 protein coding gene Chr2:151105679-151109471 (-)
C3H/HeJ MGP_C3HHeJ_G0026382
 protein coding gene Chr2:155581501-155585301 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027088
 protein coding gene Chr2:161639034-161642880 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024459
 protein coding gene Chr2:144385116-144388966 (-)
CAST/EiJ MGP_CASTEiJ_G0025843
 protein coding gene Chr2:155823927-155827646 (-)
CBA/J MGP_CBAJ_G0026360
 protein coding gene Chr2:167561809-167565603 (-)
DBA/2J MGP_DBA2J_G0026496
 protein coding gene Chr2:150010768-150014656 (-)
FVB/NJ MGP_FVBNJ_G0026462
 protein coding gene Chr2:148462569-148466385 (-)
LP/J MGP_LPJ_G0026600
 protein coding gene Chr2:157215922-157219698 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026483
 protein coding gene Chr2:171661367-171667223 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027144
 protein coding gene Chr2:155083422-155087230 (-)
PWK/PhJ MGP_PWKPhJ_G0025577
 protein coding gene Chr2:149530154-149533983 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025380
 protein coding gene Chr2:153912869-153925298 (-)
WSB/EiJ MGP_WSBEiJ_G0025913
 protein coding gene Chr2:156001130-156004906 (-)



Homology
more
  • Human Ortholog
    DEFB125, defensin beta 125
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DEFB125, defensin beta 125
  • Synonyms
    DEFB-25
  • Links
    NCBI Gene ID: 245938
    neXtProt AC: NX_Q8N687
    UniProt: Q8N687

  • Chr Location
    20p13; chr20:87250-97094 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074680 Ensembl Gene Model | MGI Sequence Detail 3895 C57BL/6J ±  kb
transcript ENSMUST00000099205 Ensembl | MGI Sequence Detail 561 Not Applicable  
polypeptide ENSMUSP00000096811 Ensembl | MGI Sequence Detail 186 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR025933 Beta-defensin
    IPR050544 Beta-defensin antimicrobial peptides
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 16
    Phenotypes 5
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory