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Defb23 Gene Detail
Summary
  • Symbol
    Defb23
  • Name
    defensin beta 23
  • Synonyms
    EG629114
  • Feature Type
    protein coding gene
  • IDs
    MGI:3644405
    NCBI Gene: 629114
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:152300975-152306540 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 75.08 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    236 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3644405
 protein coding gene Chr2:152300914-152306540 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026661
 protein coding gene Chr2:157018385-157023996 (-)
A/J MGP_AJ_G0026627
 protein coding gene Chr2:150744340-150750785 (-)
AKR/J MGP_AKRJ_G0026597
 protein coding gene Chr2:155151657-155158503 (-)
BALB/cJ MGP_BALBcJ_G0026636
 protein coding gene Chr2:151056077-151061600 (-)
C3H/HeJ MGP_C3HHeJ_G0026379
 protein coding gene Chr2:155529750-155537115 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027085
 protein coding gene Chr2:161588389-161593858 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024456
 protein coding gene Chr2:144334861-144340589 (-)
CAST/EiJ MGP_CASTEiJ_G0025840
 protein coding gene Chr2:155765293-155775035 (-)
CBA/J MGP_CBAJ_G0026357
 protein coding gene Chr2:167506152-167514459 (-)
DBA/2J MGP_DBA2J_G0026493
 protein coding gene Chr2:149962557-149968164 (-)
FVB/NJ MGP_FVBNJ_G0026459
 protein coding gene Chr2:148412407-148417851 (-)
LP/J MGP_LPJ_G0026597
 protein coding gene Chr2:157163720-157170702 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026480
 protein coding gene Chr2:171606374-171613344 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027141
 protein coding gene Chr2:155031138-155037111 (-)
PWK/PhJ MGP_PWKPhJ_G0025574
 protein coding gene Chr2:149479499-149485624 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025377
 protein coding gene Chr2:153859576-153867246 (-)
WSB/EiJ MGP_WSBEiJ_G0025910
 protein coding gene Chr2:155950360-155957095 (-)



Homology
more
  • Human Ortholog
    DEFB129, defensin beta 129
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DEFB129, defensin beta 129
  • Synonyms
    bA530N10.3, C20orf87, DEFB-29, DEFB29, hBD-29
  • Links
    NCBI Gene ID: 140881
    neXtProt AC: NX_Q9H1M3
    UniProt: Q9H1M3

  • Chr Location
    20p13; chr20:227258-229886 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Defb23
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    5 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074681 Ensembl Gene Model | MGI Sequence Detail 5566 C57BL/6J ±  kb
transcript ENSMUST00000099206 Ensembl | MGI Sequence Detail 624 Not Applicable  
polypeptide ENSMUSP00000096812 Ensembl | MGI Sequence Detail 166 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR025933 Beta-defensin
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 14
    Phenotypes 4
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory