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Ccdc188 Gene Detail
Summary
  • Symbol
    Ccdc188
  • Name
    coiled-coil domain containing 188
  • Synonyms
    Gm7873
  • Feature Type
    protein coding gene
  • IDs
    MGI:3647803
    NCBI Gene: 102638083
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:18035743-18038212 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 11.29 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3647803
 protein coding gene Chr16:18032091-18038212 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022603
 protein coding gene Chr16:15425440-15426583 (+)
A/J MGP_AJ_G0022564
 protein coding gene Chr16:14661966-14663109 (+)
AKR/J MGP_AKRJ_G0022541
 protein coding gene Chr16:15239058-15240201 (+)
BALB/cJ MGP_BALBcJ_G0022569
 protein coding gene Chr16:14810845-14811988 (+)
C3H/HeJ MGP_C3HHeJ_G0022336
 protein coding gene Chr16:15402286-15403429 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023018
 protein coding gene Chr16:15692299-15693442 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020538
 protein coding gene Chr16:14712806-14713948 (+)
CAST/EiJ MGP_CASTEiJ_G0021863
 protein coding gene Chr16:15290619-15291762 (+)
CBA/J MGP_CBAJ_G0022305
 protein coding gene Chr16:16378745-16379888 (+)
DBA/2J MGP_DBA2J_G0022437
 protein coding gene Chr16:14573144-14574287 (+)
FVB/NJ MGP_FVBNJ_G0022412
 protein coding gene Chr16:14630523-14631666 (+)
LP/J MGP_LPJ_G0022504
 protein coding gene Chr16:15209199-15210342 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022434
 protein coding gene Chr16:16031812-16032955 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023029
 protein coding gene Chr16:15173868-15175011 (+)
PWK/PhJ MGP_PWKPhJ_G0021605
 protein coding gene Chr16:14843371-14844514 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021433
 protein coding gene Chr16:15145010-15146146 (+)
WSB/EiJ MGP_WSBEiJ_G0021909
 protein coding gene Chr16:15160368-15161511 (+)



Homology
more
  • Human Ortholog
    CCDC188, coiled-coil domain containing 188
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC188, coiled-coil domain containing 188
  • Links
    NCBI Gene ID: 388849
    UniProt: H7C350

  • Chr Location
    22q11.21; chr22:20148416-20151055 (-)  GRCh38
Human Diseases
less
  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    127 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    774
  • Tissues
    9
  • cDNA Data
    1
  • Literature Summary
    1
Sequences &
Gene Models
less
  • All Sequences
    53
  • RefSeq
    21
  • UniProt
    4
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000090777 Ensembl Gene Model | MGI Sequence Detail 2470 C57BL/6J ±  kb
transcript ENSMUST00000231369 Ensembl | MGI Sequence Detail 1588 Not Applicable  
polypeptide ENSMUSP00000155981 Ensembl | MGI Sequence Detail 436 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR026617 Transmembrane and coiled-coil domain-containing protein 2/5
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
References
more
  • Summaries
    All 134
    Developmental Gene Expression 1
    Diseases 6
    Phenotypes 127
  • Earliest
    J:57757 Lindsay EA, et al., Congenital heart disease in mice deficient for the DiGeorge syndrome region [see comments]. Nature. 1999 Sep 23;401(6751):379-83
  • Latest
    J:351616 Pechous RD, et al., SARS-CoV-2 Infection Causes Heightened Disease Severity and Mortality in a Mouse Model of Down Syndrome. Biomedicines. 2024 Feb 28;12(3)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory