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Ighv10-3 Gene Detail
Summary
  • Symbol
    Ighv10-3
  • Name
    immunoglobulin heavy variable V10-3
  • Feature Type
    gene segment
  • IDs
    MGI:3648785
    NCBI Gene: 380809
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:114487061-114487507 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 62.39 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    223 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3648785
 gene segment Chr12:114487061-114487525 (-)
129S1/SvImJ MGP_129S1SvImJ_G0000072
 gene segment Chr12:117126133-117126597 (-)
A/J MGP_AJ_G0000080
 gene segment Chr12:112720799-112721263 (-)
AKR/J MGP_AKRJ_G0000079
 gene segment Chr12:116033120-116033583 (-)
BALB/cJ MGP_BALBcJ_G0000074
 gene segment Chr12:113200993-113201457 (-)
C3H/HeJ MGP_C3HHeJ_G0000080
 gene segment Chr12:116408091-116408554 (-)
C57BL/6NJ MGP_C57BL6NJ_G0000101
 gene segment Chr12:120824231-120824695 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0000054
 gene segment Chr12:109041164-109041628 (-)
CAST/EiJ MGP_CASTEiJ_G0000076
 gene segment Chr12:111142226-111142690 (-)
CBA/J MGP_CBAJ_G0000075
 gene segment Chr12:125406071-125406535 (-)
DBA/2J MGP_DBA2J_G0000078
 gene segment Chr12:112228713-112229175 (-)
FVB/NJ MGP_FVBNJ_G0000073
 gene segment Chr12:110956913-110957377 (-)
LP/J MGP_LPJ_G0000085
 gene segment Chr12:117148765-117149229 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0000082
 gene segment Chr12:128692914-128693378 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0000093
 gene segment Chr12:115410987-115411450 (-)
PWK/PhJ MGP_PWKPhJ_G0000069
 gene segment Chr12:106945645-106946109 (-)
SPRET/EiJ MGP_SPRETEiJ_G0000059
 gene segment Chr12:109674839-109675303 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IGHV3-73, immunoglobulin heavy variable 3-73
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGHV3-73, immunoglobulin heavy variable 3-73
  • Synonyms
    IGHV373, VH
  • Links
    NCBI Gene ID: 28409
    UniProt: A0A0B4J1V6

  • Chr Location
    14q32.33; chr14:106802692-106803233 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    25
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 380809 NCBI Gene Model | MGI Sequence Detail 447 C57BL/6J ±  kb
transcript M21469 GenBank | ENA | DDBJ | MGI Sequence Detail 443 Not Specified  
polypeptide A0A075B5T6 UniProt | EBI | MGI Sequence Detail 119 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR050199 Immunoglobulin Heavy Variable
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
References
more
  • Summaries
    All 8
    Gene Ontology 1
  • Earliest
    J:71617 Li J, et al., The rearranged v(h) domain of a physiologically selected anti-single-stranded dna antibody as a precursor for formation of igm and igg antibodies to diverse antigens. J Immunol. 2001 Oct 1;167(7):3746-55
  • Latest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory