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Pin1rt1 Gene Detail
Summary
  • Symbol
    Pin1rt1
  • Name
    peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1, retrogene 1
  • Synonyms
    OTTMUSG00000014964, Pin1l, Pin1-ps1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3649546
    NCBI Gene: 241593
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr2:104544271-104546724 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 54.91 cM
Strain
Comparison
more
  • SNPs within 2kb
    146 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3649546
 protein coding gene Chr2:104544232-104546724 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026220
 protein coding gene Chr2:106828923-106831277 (-)
A/J MGP_AJ_G0026181
 protein coding gene Chr2:102372304-102374579 (-)
AKR/J MGP_AKRJ_G0026161
 protein coding gene Chr2:105162217-105164617 (-)
BALB/cJ MGP_BALBcJ_G0026190
 protein coding gene Chr2:102655596-102657872 (-)
C3H/HeJ MGP_C3HHeJ_G0025941
 protein coding gene Chr2:105489265-105491696 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026641
 protein coding gene Chr2:110346489-110348754 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024028
 protein coding gene Chr2:98187655-98190194 (-)
CAST/EiJ MGP_CASTEiJ_G0025405
 protein coding gene Chr2:105995744-105998125 (-)
CBA/J MGP_CBAJ_G0025918
 protein coding gene Chr2:114129561-114132016 (-)
DBA/2J MGP_DBA2J_G0026056
 protein coding gene Chr2:101921920-101924293 (-)
FVB/NJ MGP_FVBNJ_G0026019
 protein coding gene Chr2:100903269-100905685 (-)
LP/J MGP_LPJ_G0026159
 protein coding gene Chr2:106945196-106947655 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026043
 protein coding gene Chr2:117994195-117996605 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026695
 protein coding gene Chr2:105364799-105367245 (-)
PWK/PhJ MGP_PWKPhJ_G0025140
 protein coding gene Chr2:101457189-101459811 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024941
 protein coding gene Chr2:104590008-104592408 (-)
WSB/EiJ MGP_WSBEiJ_G0025472
 protein coding gene Chr2:106094374-106096601 (-)



Homology
more
  • Human Ortholog
    PIN1, peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PIN1, peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • Synonyms
    DOD, UBL5
  • Links
    NCBI Gene ID: 5300
    neXtProt AC: NX_Q13526
    UniProt: Q13526

  • Chr Location
    19p13.2; chr19:9835257-9849689 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Pin1rt1
  • Find Mice (IMSR)
    7 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074997 Ensembl Gene Model | MGI Sequence Detail 2454 C57BL/6J ±  kb
transcript ENSMUST00000099659 Ensembl | MGI Sequence Detail 1172 Not Applicable  
polypeptide ENSMUSP00000139143 Ensembl | MGI Sequence Detail 159 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • EC
    5.2.1.8
  • InterPro Domains
    IPR046357 Peptidyl-prolyl cis-trans isomerase domain superfamily
    IPR051370 Peptidyl-prolyl cis-trans isomerase Pin1
    IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type
    IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site
    IPR001202 WW domain
    IPR036020 WW domain superfamily
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:128271 Zhu JX, et al., Identification and characterization of a novel and functional murine Pin1 isoform. Biochem Biophys Res Commun. 2007 Aug 3;359(3):529-35
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory