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Spint5 Gene Detail
Summary
  • Symbol
    Spint5
  • Name
    serine protease inhibitor, Kunitz type 5
  • Synonyms
    Gm14316
  • Feature Type
    protein coding gene
  • IDs
    MGI:3651687
    NCBI Gene: 641368
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164557225-164559988 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.27 cM
Strain
Comparison
more
  • SNPs within 2kb
    188 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651687
 protein coding gene Chr2:164557225-164559988 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026868
 protein coding gene Chr2:170205102-170207931 (+)
A/J MGP_AJ_G0026835
 protein coding gene Chr2:163252658-163255357 (+)
AKR/J MGP_AKRJ_G0026806
 protein coding gene Chr2:168103223-168105888 (+)
BALB/cJ MGP_BALBcJ_G0026844
 protein coding gene Chr2:163609924-163612621 (+)
C3H/HeJ MGP_C3HHeJ_G0026586
 protein coding gene Chr2:168465511-168468266 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027291
 protein coding gene Chr2:175135635-175138308 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024662
 protein coding gene Chr2:156659545-156661918 (+)
CAST/EiJ MGP_CASTEiJ_G0026044
 protein coding gene Chr2:168883838-168886514 (+)
CBA/J MGP_CBAJ_G0026563
 protein coding gene Chr2:181495636-181498331 (+)
DBA/2J MGP_DBA2J_G0026701
 protein coding gene Chr2:162418882-162421641 (+)
FVB/NJ MGP_FVBNJ_G0026667
 protein coding gene Chr2:160840003-160842894 (+)
LP/J MGP_LPJ_G0026803
 protein coding gene Chr2:170268591-170271290 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026686
 protein coding gene Chr2:185055280-185057983 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027348
 protein coding gene Chr2:168008971-168011730 (+)
PWK/PhJ MGP_PWKPhJ_G0025781
 protein coding gene Chr2:162017830-162020867 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025582
 protein coding gene Chr2:166911351-166913915 (+)
WSB/EiJ MGP_WSBEiJ_G0026117
 protein coding gene Chr2:168893533-168896254 (+)



Homology
more
  • Human Ortholog
    SPINT5P, serine peptidase inhibitor, Kunitz type 5, pseudogene
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPINT5P, serine peptidase inhibitor, Kunitz type 5, pseudogene
  • Synonyms
    C20orf168, dJ447F3.6
  • Links
    NCBI Gene ID: 140863

  • Chr Location
    chr20:45749920-45750074 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 641368 NCBI Gene Model | MGI Sequence Detail 2764 C57BL/6J ±  kb
transcript NM_001040055 RefSeq | MGI Sequence Detail 443 C57BL/6  
polypeptide NP_001035144 RefSeq | MGI Sequence Detail 105 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR050098 Kunitz-type Serine Protease Inhibitor
    IPR002223 Pancreatic trypsin inhibitor Kunitz domain
    IPR036880 Pancreatic trypsin inhibitor Kunitz domain superfamily
    IPR020901 Proteinase inhibitor I2, Kunitz, conserved site
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 14
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:295177 Robertson MJ, et al., Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets. BMC Biol. 2020 Aug 19;18(1):103
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory