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Tmt1a3 Gene Detail
Summary
  • Symbol
    Tmt1a3
  • Name
    thiol methyltransferase 1A3
  • Synonyms
    Gm10035, Mettl7a3
  • Feature Type
    protein coding gene
  • IDs
    MGI:3710670
    NCBI Gene: 668178
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr15:100232810-100238256 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    242 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3710670
 protein coding gene Chr15:100232687-100246267 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0022310
 protein coding gene Chr15:98160617-98172140 (+)
AKR/J MGP_AKRJ_G0022286
 protein coding gene Chr15:101187503-101205875 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0022085
 protein coding gene Chr15:101295332-101303389 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022760
 protein coding gene Chr15:106053363-106099712 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020288
 protein coding gene Chr15:94047063-94053034 (+)
CAST/EiJ MGP_CASTEiJ_G0021610
 protein coding gene Chr15:102136962-102146069 (+)
CBA/J MGP_CBAJ_G0022054
 protein coding gene Chr15:109766161-109806255 (+)
DBA/2J MGP_DBA2J_G0022180
 protein coding gene Chr15:97580198-97594978 (+)
FVB/NJ MGP_FVBNJ_G0022159
 protein coding gene Chr15:96573727-96590701 (+)
LP/J MGP_LPJ_G0022252
 protein coding gene Chr15:102381033-102389315 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022181
 protein coding gene Chr15:113517230-113528007 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022777
 protein coding gene Chr15:101285408-101295848 (+)
PWK/PhJ MGP_PWKPhJ_G0021349
 protein coding gene Chr15:97770045-97779478 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0021659
 protein coding gene Chr15:101819529-101827371 (+)



Homology
more
  • Human Ortholog
    TMT1A, thiol methyltransferase 1A
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMT1A, thiol methyltransferase 1A
  • Synonyms
    AAM-B, AAMB, METTL7A
  • Links
    NCBI Gene ID: 25840
    neXtProt AC: NX_Q9H8H3
    UniProt: Q9H8H3

  • Chr Location
    12q13.12; chr12:50923472-50932510 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000058057 Ensembl Gene Model | MGI Sequence Detail 5447 C57BL/6J ±  kb
transcript ENSMUST00000075420 Ensembl | MGI Sequence Detail 1652 Not Applicable  
polypeptide ENSMUSP00000074875 Ensembl | MGI Sequence Detail 244 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:7461486
References
more
  • Summaries
    All 32
    Diseases 1
    Gene Ontology 2
    Phenotypes 21
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory