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Mageb5b Gene Detail
Summary
  • Symbol
    Mageb5b
  • Name
    MAGE family member B5B
  • Synonyms
    Gm14781
  • Feature Type
    protein coding gene
  • IDs
    MGI:3712084
    NCBI Gene: 629542
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:90675800-90679277 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 40.45 cM
Strain
Comparison
more
  • SNPs within 2kb
    51 from dbSNP Build 142
  • Strain Annotations
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3712084
 protein coding gene ChrX:90667849-90679277 (+)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0035867
 protein coding gene ChrX:86790684-86794158 (+)
C3H/HeJ MGP_C3HHeJ_G0035576
 protein coding gene ChrX:88279107-88282581 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036395
 protein coding gene ChrX:90670236-90673710 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0035794
 protein coding gene ChrX:88717703-88721177 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0034562
 protein coding gene ChrX:71066299-71069776 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034393
 protein coding gene ChrX:74093965-74097436 (-)
WSB/EiJ MGP_WSBEiJ_G0035004
 protein coding gene ChrX:86450083-86453555 (+)



Homology
more
  • Human Ortholog
    MAGEB5, MAGE family member B5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAGEB5, MAGE family member B5
  • Synonyms
    CT3.3, MAGE-B5
  • Links
    NCBI Gene ID: 347541
    neXtProt AC: NX_Q9BZ81
    UniProt: Q9BZ81

  • Chr Location
    Xp21.3
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from multigenic genotypes
    3 phenotype references
Mice hemizygous for a deletion of a 30 kb deletion including Mageb5 and a null allele of Mageb5b exhibit normal male fertility despite slightly elongated sperm.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000064129 Ensembl Gene Model | MGI Sequence Detail 3478 C57BL/6J ±  kb
transcript ENSMUST00000078469 Ensembl | MGI Sequence Detail 1360 Not Applicable  
polypeptide ENSMUSP00000077562 Ensembl | MGI Sequence Detail 366 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002190 MAGE homology domain
    IPR041898 MAGE homology domain, winged helix WH1 motif
    IPR041899 MAGE homology domain, winged helix WH2 motif
    IPR037445 Melanoma-associated antigen
    IPR021072 Melanoma associated antigen, N-terminal
Other
Accession IDs
less
MGI:6448165
References
more
  • Summaries
    All 12
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
  • Latest
    J:334464 Stark-Dykema ER, et al., X-linked palindromic gene families 4930567H17Rik and Mageb5 are dispensable for male mouse fertility. Sci Rep. 2022 May 20;12(1):8554
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory