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Dynlt1a Gene Detail
Summary
  • Symbol
    Dynlt1a
  • Name
    dynein light chain Tctex-type 1A
  • Feature Type
    protein coding gene
  • IDs
    MGI:3807506
    NCBI Gene: 100310872
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:6356619-6367749 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 3.88 cM
Strain
Comparison
more
  • SNPs within 2kb
    158 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3807506
 protein coding gene Chr17:6356615-6367775 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023115
 protein coding gene Chr17:3620515-3626852 (+)
A/J MGP_AJ_G0023084
 protein coding gene Chr17:3709216-3725574 (+)
AKR/J MGP_AKRJ_G0023050
 protein coding gene Chr17:3926117-3928171 (-)
BALB/cJ MGP_BALBcJ_G0023086
 protein coding gene Chr17:3736782-3742486 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0031861
 protein coding gene Chr6:143493785-143494929 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021032
 protein coding gene Chr17:3180031-3186525 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0022813
 protein coding gene Chr17:4185601-4187615 (-)
DBA/2J MGP_DBA2J_G0022950
 protein coding gene Chr17:3606497-3608551 (-)
FVB/NJ MGP_FVBNJ_G0022923
 protein coding gene Chr17:3291145-3301799 (-)
LP/J MGP_LPJ_G0023016
 protein coding gene Chr17:3567503-3750915 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0023553
 protein coding gene Chr17:3925061-3927075 (-)
PWK/PhJ MGP_PWKPhJ_G0022108
 protein coding gene Chr17:3308981-3316265 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0022416
 protein coding gene Chr17:3809563-3990799 (-)



Homology
more
  • Human Ortholog
    DYNLT1, dynein light chain Tctex-type 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DYNLT1, dynein light chain Tctex-type 1
  • Synonyms
    CW-1, TCTEL1, tctex-1, TCTEX1
  • Links
    NCBI Gene ID: 6993
    neXtProt AC: NX_P63172
    UniProt: P63172

  • Chr Location
    6q25.3; chr6:158636474-158644743 (-)  GRCh38
Human Diseases
less
  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    349 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100310872 NCBI Gene Model | MGI Sequence Detail 11131 C57BL/6J ±  kb
transcript NM_001166629 RefSeq | MGI Sequence Detail 4978 Not Specified  
polypeptide NP_001160101 RefSeq | MGI Sequence Detail 113 Not Specified  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3
References
more
  • Summaries
    All 360
    Developmental Gene Expression 1
    Diseases 6
    Gene Ontology 2
    Phenotypes 349
  • Earliest
    J:30229 Davisson MT, et al., Segmental trisomy as a mouse model for Down syndrome. Prog Clin Biol Res. 1993;384:117-33
  • Latest
    J:354984 Emili M, et al., Reversal of neurodevelopmental impairment and cognitive enhancement by pharmacological intervention with the polyphenol polydatin in a Down syndrome model. Neuropharmacology. 2024 Sep 27;261:110170
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory