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Igkv6-25 Gene Detail
Summary
  • Symbol
    Igkv6-25
  • Name
    immunoglobulin kappa chain variable 6-25
  • Synonyms
    Gm16943
  • Feature Type
    gene segment
  • IDs
    MGI:4439867
    NCBI Gene: 381784
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:70192417-70192941 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 31.81 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    240 from dbSNP Build 142
  • Strain Annotations
    4
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4439867
 gene segment Chr6:70192384-70192941 (+)
129S1/SvImJ MGP_129S1SvImJ_G0000176
 gene segment Chr6:70806021-70807493 (-)
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0000208
 gene segment Chr6:72365713-72366270 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0000192
 gene segment Chr6:69666095-69666652 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IGKV4-1, immunoglobulin kappa variable 4-1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGKV4-1, immunoglobulin kappa variable 4-1
  • Synonyms
    B3, IGKV41
  • Links
    NCBI Gene ID: 28908
    UniProt: P06312

  • Chr Location
    2p11.2; chr2:88885397-88886153 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    10
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 381784 NCBI Gene Model | MGI Sequence Detail 525 C57BL/6J ±  kb
polypeptide A0A140T8N7 UniProt | EBI | MGI Sequence Detail 115 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003599 Immunoglobulin subtype
    IPR050150 Immunoglobulin Variable Light Chain
    IPR013106 Immunoglobulin V-set domain
References
more
  • Summaries
    All 7
    Gene Ontology 1
  • Earliest
    J:35043 Kelley DE, et al., Functional significance and evolutionary development of the 5'-terminal regions of immunoglobulin variable-region genes. Cell. 1982 Jun;29(2):681-9
  • Latest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory